Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …

Over the last three decades, numerous aptamer-based biosensors have been reported. The
basis of these sensors is the selective binding of target analytes by aptamers. In the last few …

Due to their relative synthetic and chemical simplicity compared to antibodies, aptamers
afford enhanced stability and functionality for the detection of environmental contaminants …

Nanozymes are engineered nanomaterials with enzyme-like activities. Over the past
decade, impressive progresses on nanozymes in biosensing have been made due to their …

Background Nucleic acid aptamers, defined as small functional nucleic acids that can
selectively bind to a specific target, have become one of the main bio-recognition elements …

Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

Mycotoxin contamination in food products can easily cause serious health hazards and
economic losses to human beings. How to accurately detect and effectively control …

Label-free optical biosensors are an intriguing option for the analyses of many analytes, as
they offer several advantages such as high sensitivity, direct and real-time measurement in …

In this manuscript, we compare different analytical methodologies to validate or disprove the
binding capabilities of aptamer sequences. This was prompted by the lack of a universally …