[HTML][HTML] Emerging wastewater contaminant metformin causes intersex and reduced fecundity in fish
NJ Niemuth, RD Klaper - Chemosphere, 2015 - Elsevier
The occurrence of intersex fish, where male reproductive tissues show evidence of
feminization, have been found in freshwater systems around the world, indicating the …
feminization, have been found in freshwater systems around the world, indicating the …
Ecotoxicological effects, water quality standards and risk assessment for the anti-diabetic metformin
Metformin (MET) is among the most consumed pharmaceuticals worldwide. This compound
has been frequently detected in fresh surface water. However, ecotoxicological information …
has been frequently detected in fresh surface water. However, ecotoxicological information …
Metformin-induced endocrine disruption and oxidative stress of Oryzias latipes on two-generational condition
JW Lee, YJ Shin, H Kim, H Kim, J Kim, SA Min… - Journal of Hazardous …, 2019 - Elsevier
Metformin has been treated for diabetes (type 2). Nowadays, this compound is frequently
found in ambient water, influent/effluent of a wastewater treatment plant. To evaluate the …
found in ambient water, influent/effluent of a wastewater treatment plant. To evaluate the …
Role of kinetic models in drug stability
Kinetic models are studied to determine their role in stability and release kinetics of drugs.
The mathematical models that have been widely used are zero-order kinetic model, first …
The mathematical models that have been widely used are zero-order kinetic model, first …
Mild chemo-photothermal synergistic therapy for tumors based on gold-nanoparticles coupled with metformin
T Yang, H Wang, Q Zhou, W Huang… - ACS Applied Nano …, 2023 - ACS Publications
The past decades have witnessed great achievements in the synergistic therapy for tumors,
especially chemo-photothermal synergistic therapy. However, due to the high working …
especially chemo-photothermal synergistic therapy. However, due to the high working …
Occurrence, impact, analysis and treatment of metformin and guanylurea in coastal aquatic environments of Canada, USA and Europe
This review discusses the occurrence, impact, analysis and treatment of metformin and
guanylurea in coastal aquatic environments of Canada, USA and Europe. Metformin, a …
guanylurea in coastal aquatic environments of Canada, USA and Europe. Metformin, a …
Age-dependent effects in fathead minnows from the anti-diabetic drug metformin
The anti-diabetic drug metformin is thought to be the pharmaceutical most deposited into the
aquatic environment by mass at up to 6 tons per year from individual WWTPs in urban areas …
aquatic environment by mass at up to 6 tons per year from individual WWTPs in urban areas …
Metformin-induced alterations in gills of the freshwater fish Astyanax lacustris (Lütken, 1875) detected by histological and scanning electron microscopy
PA Barbieri, IP Mari-Ribeiro, L Lupepsa, AAS Gigliolli… - Ecotoxicology, 2022 - Springer
The antidiabetic drug metformin is widely prescribed and found in different concentrations in
the environment around the world, raising concern about potential impacts on aquatic life …
the environment around the world, raising concern about potential impacts on aquatic life …
Theoretical and experimental investigation on the intercalation of metformin into layered clay minerals
This work introduces a comparative study on the use of two layered clays, a natural
Wyoming montmorillonite (commercialized as Cloisite® Na; Mt) and a synthetic hectorite …
Wyoming montmorillonite (commercialized as Cloisite® Na; Mt) and a synthetic hectorite …
The combination of metformin and valproic acid has a greater anti-tumoral effect on prostate cancer growth in vivo than either drug alone
Background/Aim: The hypoglycemic drug metformin (MET) and the anti-epileptic drug
valproic acid (VPA) have individually shown anti-tumor effects in prostate cancer in vitro. The …
valproic acid (VPA) have individually shown anti-tumor effects in prostate cancer in vitro. The …