General adaptation in critical illness 1: The glucocorticoid signaling system as master rheostat of homeostatic corrections in concerted action with nuclear factor-κB

GU Meduri, GP Chrousos - Stress: Immunology and Inflammation, 2024 - Elsevier
In critical illness, homeostatic corrections, which represent the culmination of hundreds of
millions of years of evolution, are primarily regulated by the glucocorticoid (GC)-activated …