BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

B Lu, G Nagappan, X Guan, PJ Nathan… - Nature Reviews …, 2013 - nature.com
Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …

A compensatory role for declarative memory in neurodevelopmental disorders

MT Ullman, MY Pullman - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Most research on neurodevelopmental disorders has focused on their abnormalities.
However, what remains intact may also be important. Increasing evidence suggests that …

Involvement of the dorsal and ventral attention networks in oddball stimulus processing: A meta‐analysis

H Kim - Human brain mapping, 2014 - Wiley Online Library
The aim of this study was to provide the first, comprehensive meta‐analysis of the
neuroimaging literature regarding greater neural responses to a deviant stimulus in a stream …

BDNF–TrkB receptor regulation of distributed adult neural plasticity, memory formation, and psychiatric disorders

R Andero, DC Choi, KJ Ressler - Progress in molecular biology and …, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) and its single transmembrane receptor,
tropomysin-related kinase B (TrkB), are essential for adult synaptic plasticity and the …

Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function

AL Teixeira, IG Barbosa, BS Diniz… - Biomarkers in …, 2010 - Taylor & Francis
Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the
CNS, where it plays several pivotal roles in synaptic plasticity and neuronal survival. As a …

Impact of brain‐derived neurotrophic factor genetic polymorphism on cognition: A systematic review

YL Toh, T Ng, M Tan, A Tan, A Chan - Brain and behavior, 2018 - Wiley Online Library
Introduction Brain‐derived neurotrophic factor (BDNF) has an important role in the
neurogenesis and neuroplasticity of the brain. This systematic review was designed to …

Impact of the BDNF Val66Met polymorphism on cognition: implications for behavioral genetics

I Dincheva, CE Glatt, FS Lee - The Neuroscientist, 2012 - journals.sagepub.com
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin growth factor
family and is implicated as a modulator of neuronal survival and differentiation, synaptic …

BDNF Val66Met and cognition: all, none, or some? A meta‐analysis of the genetic association

SD Mandelman, EL Grigorenko - Genes, Brain and Behavior, 2012 - Wiley Online Library
The Val66Met, G196A (rs6265) polymorphism in the brain‐derived neurotrophic factor gene,
BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet …

Effect of BDNF val66met polymorphism on declarative memory and its neural substrate: A meta-analysis

JP Kambeitz, S Bhattacharyya… - Neuroscience & …, 2012 - Elsevier
Brain derived neurotrophic factor (BDNF) is a critical component of the molecular
mechanism of memory formation. Variation in the BDNF gene, particularly the rs6265 …

Executive dysfunction in euthymic bipolar disorder patients and its association with plasma biomarkers

IG Barbosa, NP Rocha, RB Huguet, RA Ferreira… - Journal of affective …, 2012 - Elsevier
BACKGROUND: Despite the old Kraepelinean concept that bipolar disorder (BD) does not
evolve with cognitive decline, the presence of cognitive impairment, especially executive …