A systematic review of biomarkers to detect active tuberculosis
Millions of cases of tuberculosis (TB) go undiagnosed each year. Better diagnostic tools are
urgently needed. Biomarker-based or multiple marker biosignature-based tests, ideally …
urgently needed. Biomarker-based or multiple marker biosignature-based tests, ideally …
[HTML][HTML] Point of care diagnostics for tuberculosis
The goals of the End TB strategy, which aims to achieve a 90% reduction in tuberculosis
(TB) incidence and a 95% reduction in TB mortality by 2035, will not be achieved without …
(TB) incidence and a 95% reduction in TB mortality by 2035, will not be achieved without …
[HTML][HTML] iSCAN: An RT-LAMP-coupled CRISPR-Cas12 module for rapid, sensitive detection of SARS-CoV-2
The COVID-19 pandemic caused by SARS-CoV-2 affects all aspects of human life.
Detection platforms that are efficient, rapid, accurate, specific, sensitive, and user friendly are …
Detection platforms that are efficient, rapid, accurate, specific, sensitive, and user friendly are …
[HTML][HTML] Efficient, rapid, and sensitive detection of plant RNA viruses with one-pot RT-RPA–CRISPR/Cas12a assay
Most viruses that infect plants use RNA to carry their genomic information; timely and robust
detection methods are crucial for efficient control of these diverse pathogens. The RNA …
detection methods are crucial for efficient control of these diverse pathogens. The RNA …
A novel miniature CRISPR-Cas13 system for SARS-CoV-2 diagnostics
Rapid, point-of-care (POC) diagnostics are essential to mitigate the impacts of current (and
future) epidemics; however, current methods for detecting severe acute respiratory …
future) epidemics; however, current methods for detecting severe acute respiratory …
Highly Specific and Rapid Detection of hepatitis C virus using RT-LAMP-coupled CRISPR–Cas12 assay
N Kham-Kjing, N Ngo-Giang-Huong, K Tragoolpua… - Diagnostics, 2022 - mdpi.com
Hepatitis C virus (HCV) infection can be cured with pan-genotypic direct-acting antiviral
agents. However, identifying individuals with current hepatitis C remains a major challenge …
agents. However, identifying individuals with current hepatitis C remains a major challenge …
Advances in the molecular diagnosis of tuberculosis: from probes to genomes
Tuberculosis, disease caused by Mycobacterium tuberculosis, is currently the leading cause
of death by a single infectious agent worldwide. Early, rapid and accurate identification of M …
of death by a single infectious agent worldwide. Early, rapid and accurate identification of M …
CLEVER assay: A visual and rapid RNA extraction‐free detection of SARS‐CoV‐2 based on CRISPR‐Cas integrated RT‐LAMP technology
Aim The current scenario of COVID‐19 pandemic has presented an almost insurmountable
challenge even for the most sophisticated hospitals equipped with modern biomedical …
challenge even for the most sophisticated hospitals equipped with modern biomedical …
[HTML][HTML] Microarray expression profile of circular RNAs in peripheral blood mononuclear cells from active tuberculosis patients
ZK Huang, FY Yao, JQ Xu, Z Deng, RG Su… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Dysregulated expression of circular RNAs (circRNAs) was demonstrated
to be implicated in many diseases. Here, we aimed to determine circRNA profile in …
to be implicated in many diseases. Here, we aimed to determine circRNA profile in …
A Loop-Mediated Isothermal Amplification (LAMP) Assay Specific to Trichomonas tenax Is Suitable for Use at Point-of-Care
MA Matthew, J Christie, N Yang, C Yao - Microorganisms, 2022 - mdpi.com
Trichomonas tenax is a flagellated protozoan that inhabits the human and canine oral cavity
in patients with poor oral hygiene and periodontal disease. The loop-mediated isothermal …
in patients with poor oral hygiene and periodontal disease. The loop-mediated isothermal …