The therapeutic potential of mesenchymal stem cells for cardiovascular diseases

Y Guo, Y Yu, S Hu, Y Chen, Z Shen - Cell Death & Disease, 2020 - nature.com
Mesenchymal stem cells (MSCs) are derived from a wide range of sources and easily
isolated and cultured. MSCs have the capacity for in vitro amplification and self-renewal, low …

Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy

VV Maldonado, NH Patel, EE Smith, CL Barnes… - Journal of biological …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

Mesenchymal stem cells improve healing of diabetic foot ulcer

Y Cao, X Gang, C Sun, G Wang - Journal of diabetes research, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs), an ideal cell source for regenerative therapy with no
ethical issues, play an important role in diabetic foot ulcer (DFU). Growing evidence has …

Cell therapy in patients with heart failure: a comprehensive review and emerging concepts

R Bolli, M Solankhi, XL Tang… - Cardiovascular research, 2022 - academic.oup.com
This review summarizes the results of clinical trials of cell therapy in patients with heart
failure (HF). In contrast to acute myocardial infarction (where results have been consistently …

Umbilical cord mesenchymal stromal cell transplantations: a systemic analysis of clinical trials

A Can, FT Celikkan, O Cinar - Cytotherapy, 2017 - Elsevier
The advances and success of umbilical cord–derived mesenchymal stromal cells (UC-
MSCs) in experimental disease animal models have fueled the development of targeted …

Recent progress in stem cell modification for cardiac regeneration

H Lemcke, N Voronina, G Steinhoff… - Stem Cells …, 2018 - Wiley Online Library
During the past decades, stem cell‐based therapy has acquired a promising role in
regenerative medicine. The application of novel cell therapeutics for the treatment of …

Functionally improved mesenchymal stem cells to better treat myocardial infarction

Z Chen, L Chen, C Zeng, WE Wang - Stem cells international, 2018 - Wiley Online Library
Myocardial infarction (MI) is one of the leading causes of death worldwide. Mesenchymal
stem cell (MSC) transplantation is considered a promising approach and has made …

The application of umbilical cord‐derived MSCs in cardiovascular diseases

Y Chen, H Shen, Y Ding, Y Yu, L Shao… - Journal of Cellular and …, 2021 - Wiley Online Library
Transplantation of stem cells is a promising, emerging treatment for cardiovascular diseases
in the modern era. Mesenchymal stem cells (MSCs) derived from the umbilical cord are one …

[HTML][HTML] Intramyocardial transplantation of umbilical cord mesenchymal stromal cells in chronic ischemic cardiomyopathy: a controlled, randomized clinical trial (HUC …

AT Ulus, C Mungan, M Kurtoglu… - … journal of stem …, 2020 - synapse.koreamed.org
Methods and Results Fifty-four patients who were randomized to receive HUC-MSCs (23×
10 6)(n= 26) or BM-MNCs (70× 10 7)(n= 12) in combination with CABG surgery. The control …

Fibrin-Enriched Cardiac Extracellular Matrix Hydrogel Promotes In Vitro Angiogenesis

R Shaik, J Xu, Y Wang, Y Hong… - ACS biomaterials science …, 2023 - ACS Publications
Angiogenesis is essential for cardiac repair after myocardial infarction. Promoting
angiogenesis has been demonstrated as an effective approach for myocardial infarction …