[HTML][HTML] Innate immune evasion by human respiratory RNA viruses

M Kikkert - Journal of innate immunity, 2020 - karger.com
The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

Host immune response to influenza A virus infection

X Chen, S Liu, MU Goraya, M Maarouf… - Frontiers in …, 2018 - frontiersin.org
Influenza A viruses (IAVs) are contagious pathogens responsible for severe respiratory
infection in humans and animals worldwide. Upon detection of IAV infection, host immune …

Evolution of influenza a virus by mutation and re-assortment

W Shao, X Li, MU Goraya, S Wang… - International journal of …, 2017 - mdpi.com
Influenza A virus (IAV), a highly infectious respiratory pathogen, has continued to be a
significant threat to global public health. To complete their life cycle, influenza viruses have …

[HTML][HTML] Acute infection of viral pathogens and their innate immune escape

KR Rai, P Shrestha, B Yang, Y Chen, S Liu… - Frontiers in …, 2021 - frontiersin.org
Viral infections can cause rampant disease in human beings, ranging from mild to acute, that
can often be fatal unless resolved. An acute viral infection is characterized by sudden or …

[HTML][HTML] Vaccine development: From concept to early clinical testing

AL Cunningham, N Garçon, O Leo, LR Friedland… - Vaccine, 2016 - Elsevier
In the 21st century, an array of microbiological and molecular allow antigens for new
vaccines to be specifically identified, designed, produced and delivered with the aim of …

Respiratory antiviral immunity and immunobiotics: beneficial effects on inflammation-coagulation interaction during influenza virus infection

H Zelaya, S Alvarez, H Kitazawa, J Villena - Frontiers in immunology, 2016 - frontiersin.org
Influenza virus (IFV) is a major respiratory pathogen of global importance, and the cause of a
high degree of morbidity and mortality, especially in high-risk populations such as infants …

RUNX1 inhibits the antiviral immune response against influenza A virus through attenuating type I interferon signaling

Y Hu, Q Pan, K Zhou, Y Ling, H Wang, Y Li - Virology journal, 2022 - Springer
Abstract Background Influenza A viruses (IAVs) are zoonotic, segmented negative-stranded
RNA viruses. The rapid mutation of IAVs results in host immune response escape and …

[HTML][HTML] Role of the intestinal microbiota in the immunomodulation of influenza virus infection

CJ Chen, GH Wu, RL Kuo, SR Shih - Microbes and Infection, 2017 - Elsevier
Prevention and treatment measures against influenza virus infection remain limited, and
alternative host protection strategies are badly needed. In this review, we discuss the …

Zinc finger CCCH-type antiviral protein 1 restricts the viral replication by positively regulating type I interferon response

B Zhang, MU Goraya, N Chen, L Xu, Y Hong… - Frontiers in …, 2020 - frontiersin.org
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) is a host antiviral factor that can
repress translation and promote degradation of specific viral mRNAs. In this study, we found …

Review of mathematical modeling of the inflammatory response in lung infections and injuries

SB Minucci, RL Heise, AM Reynolds - Frontiers in Applied …, 2020 - frontiersin.org
Lung inflammation may occur due to viral and bacterial infections, structural damage, or
inhalation of dangerous particles. These injuries may be quickly resolved by the immune …