System Xc −/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy
FJ Li, HZ Long, ZW Zhou, HY Luo, SG Xu… - Frontiers in …, 2022 - frontiersin.org
The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …
Ferroptosis and its role in chronic diseases
W Hu, K Liang, H Zhu, C Zhao, H Hu, S Yin - Cells, 2022 - mdpi.com
Ferroptosis, which has been widely associated with many diseases, is an iron-dependent
regulated cell death characterized by intracellular lipid peroxide accumulation. It exhibits …
regulated cell death characterized by intracellular lipid peroxide accumulation. It exhibits …
Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy
N Xing, Q Du, S Guo, G Xiang, Y Zhang, X Meng… - Cell Death …, 2023 - nature.com
Lung cancer is a common malignant tumor that occurs in the human body and poses a
serious threat to human health and quality of life. The existing treatment methods mainly …
serious threat to human health and quality of life. The existing treatment methods mainly …
Ferroptosis in non-small cell lung cancer: progression and therapeutic potential on it
J Zou, L Wang, H Tang, X Liu, F Peng… - International Journal of …, 2021 - mdpi.com
As a main subtype of lung cancer, the current situation of non-small cell lung cancer
(NSCLC) remains severe worldwide with a 19% survival rate at 5 years. As the conventional …
(NSCLC) remains severe worldwide with a 19% survival rate at 5 years. As the conventional …
Artesunate inhibits the cell growth in colorectal cancer by promoting ROS-dependent cell senescence and autophagy
Z Huang, S Gan, X Zhuang, Y Chen, L Lu, Y Wang… - Cells, 2022 - mdpi.com
Although artesunate has been reported to be a promising candidate for colorectal cancer
(CRC) treatment, the underlying mechanisms and molecular targets of artesunate are yet to …
(CRC) treatment, the underlying mechanisms and molecular targets of artesunate are yet to …
[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …
Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy
S Li, A Wang, Y Wu, S He, W Shuai… - Immunological …, 2024 - Wiley Online Library
Non‐small‐cell lung cancer (NSCLC), which has a high rate of metastatic spread and drug
resistance, is the most common subtype of lung cancer. Therefore, NSCLC patients have a …
resistance, is the most common subtype of lung cancer. Therefore, NSCLC patients have a …
Regulated cell death in cancer: from pathogenesis to treatment
L Gong, D Huang, Y Shi, Z Liang, H Bu - Chinese Medical Journal, 2023 - mednexus.org
Regulated cell death (RCD), including apoptosis, pyroptosis, necroptosis, and ferroptosis, is
regulated by a series of evolutionarily conserved pathways, and is required for development …
regulated by a series of evolutionarily conserved pathways, and is required for development …
[HTML][HTML] Artesunate: A review of its therapeutic insights in respiratory diseases
J Zhang, Y Li, J Wan, M Zhang, C Li, J Lin - Phytomedicine, 2022 - Elsevier
Background Artesunate, as a semi-synthetic artemisinin derivative of sesquiterpene lactone,
is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent …
is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent …
Lycopene alleviates multiple-mycotoxin-induced toxicity by inhibiting mitochondrial damage and ferroptosis in the mouse jejunum
J Lin, C Zuo, T Liang, Y Huang, P Kang, K Xiao… - Food & Function, 2022 - pubs.rsc.org
Multiple mycotoxins contamination in foods and feeds threatens human and animal health
after they accumulate in the food chain, producing various toxic effects. The common …
after they accumulate in the food chain, producing various toxic effects. The common …