During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

An improved mechanistic understanding of the adaptational processes mounted during
mammalian reproduction is emerging. Intricate pathways occurring at the fetomaternal …

Zika virus (ZIKV) infection during pregnancy is linked to severe birth defects, but mother-to-
fetus transmission routes are unknown. We infected different primary cell types from mid-and …

Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …

BACKGROUND Recurrent miscarriage and pre-eclampsia are common reproductive
disorders, but their causes are often unknown. Recent evidence has provided new insight …

The chemokine-mediated recruitment of effector T cells to sites of inflammation is a central
feature of the immune response. The extent to which chemokine expression levels are …

Trophoblasts, the specialized cells of the placenta, play a major role in implantation and
formation of the maternal-fetal interface. Through an unusual differentiation process …

The complexity of the events of embryo implantation and placentation is exemplified by the
number and range of cytokines with demonstrated roles in these processes. Disturbance of …

Successful implantation is an absolute requirement for the reproduction of species, including
humans. The process by which a foreign blastocyst is accepted by the maternal …