Purpose Garcinia kola is a medicinal plant commonly known as bitter kola. It is utilised in
ethnomedicine for the treatment of diarrhoea, bronchitis, bacterial infection, cough, hepatitis …

Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …

Glutamate receptors play a crucial role in the central nervous system and are implicated in
different brain disorders. They play a significant role in the pathogenesis of …

Methotrexate (MTX) is an effective antineoplastic drug associated with wide organ toxicity.
Accumulating evidence implicates oxidative stress to be a leading underlying mechanism of …

Kolaviron is a mixture of biflavonoids found in the nut of the West African edible seed
Garcinia kola, and it has been reported to exhibit a wide range of pharmacological activities …

In Alzheimer's disease (AD) basal forebrain cholinergic neurons appear to be targeted
primarily in early stages of the disease. Scopolamine (muscarinic receptor antagonist) has …

Multiple sclerosis is a demyelinating condition of the central nervous system which
commonly affects young adults. Kolaviron, a biflavonoid isolate of Garcinia kola, has been …

Objectives Oxidative stress is the most common factor mediating environmental chemical-
induced health adversities. Recently, an exponential rise in the use of phytochemicals as an …

This study investigated the effects of post-treatment with kolaviron on a 2-Vessel Occlusion
(2-VO) model of cerebral ischemia/reperfusion (I/R) injury in rats to ascertain its level of …

Comorbidities in human beings signify the numerous risk factors that increase the
incidences of neuro-and cardio-metabolic disorders. Experimental models depicting …