Oxidative stress is important in the pathophysiology of obesity, altering regulatory factors of
mitochondrial activity, modifying the concentration of inflammation mediators associated with …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Resveratrol is a nutraceutical with several therapeutic effects. It has been shown to mimic
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …

Sirtuins are class III histone deacetylases, whose enzymatic activity is dependent on NAD+
as a cofactor. Sirtuins are reported to modulate numerous activities by controlling gene …

Systems medicine has a mechanism-based rather than a symptom-or organ-based
approach to disease and identifies therapeutic targets in a nonhypothesis-driven manner. In …

Dietary polyphenols have been widely investigated as antidiabetic agents in cell, animals,
human study, and clinical trial. The number of publication (Indexed by Web of Science) on …

Herbal medicine, phytomedicine or botanical medicine are synonymous, utilizes plants
intended for medicinal purposes. Medicinal use of herbal medicine in the treatment and …

Adipose tissue regulates numerous physiological processes, and its dysfunction in obese
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …

Epidemiological studies have implied that diabetes mellitus (DM) will become an epidemic
accompany with metabolic and endocrine disorders worldwide. Most of DM patients are …

Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …