In this review we outline the unique effects of the autacoid adenosine in the kidney.
Adenosine is present in the cytosol of renal cells and in the extracellular space of normoxic …

The kidney displays highly efficient autoregulation so that under steady-state conditions
renal blood flow (RBF) is independent of blood pressure over a wide range of pressure …

We searched for synchronization among autoregulation mechanisms using wavelet
transforms applied to tubular pressure recordings in nephron pairs from the surface of rat …

We have developed a highly detailed mathematical model for the urine concentrating
mechanism (UCM) of the rat kidney outer medulla (OM). The model simulates preferential …

Tubuloglomerular feedback and the myogenic mechanism form an ensemble in renal
afferent arterioles that regulate single-nephron blood flow and glomerular filtration. Each …

In addition to the excretion of metabolic waste and toxin, the kidney plays an indispensable
role in regulating the balance of water, electrolyte, acid–base, and blood pressure. For the …

Mice deficient for adenosine A1 receptors (A1AR) lack tubuloglomerular feedback (TGF). In
vivo micropuncture experiments were performed under anesthesia in A1AR-deficient and …

We present an overview of currently available resources in renal systems physiology and
indicate directions for development toward the renal physiome. After a brief resumé of …

To help elucidate the causes of irregular tubular flow oscillations found in the nephrons of
spontaneously hypertensive rats (SHR), we have conducted a bifurcation analysis of a …

Mathematical models have played an essential role in elucidating various functions of the
kidney, including the mechanism by which the avian and mammalian kidney can produce a …