Human islet isolation: semi-automated and manual methods

M Paget, H Murray, CJ Bailey… - Diabetes and Vascular …, 2007 - journals.sagepub.com
Large yields of high-viability human islets are necessary to service the expanding
programmes of islet transplantation worldwide; similarly, there is an increasing demand from …

[HTML][HTML] Tacrolimus inhibits the revascularization of isolated pancreatic islets

R Nishimura, S Nishioka, I Fujisawa, H Shiku… - PLoS …, 2013 - journals.plos.org
Aims Immunosuppressive drugs could be crucial factors for a poor outcome after islet
allotransplantation. Unlike rapamycin, the effects of tacrolimus, the current standard …

Isolation and purification of islet cells from adult pigs

AY Qiao, WH Zhang, XJ Chen, J Zhang, GH Xiao… - Transplantation …, 2010 - Elsevier
We used in situ perfusion and a multiple-organ harvesting technique to collect islets from
adult pig pancreata. The tissues were digested with collagenase P followed by purification in …

[HTML][HTML] Optimization of dye solutions for detecting damaged pancreatic tissues during islet isolation procedures

T Imura, A Inagaki, Y Igarashi, M Goto - Plos one, 2021 - journals.plos.org
We previously reported that dye was effective to prevent the leakage of enzyme solutions
from pancreatic glands during an islet isolation procedure. However, the dye used for islet …

FK506 对糖尿病小鼠胰岛移植物功能及再血管化的影响

莫玲斐, 杜成友, 潘龙 - 上海交通大学学报(医学版), 2013 - xuebao.shsmu.edu.cn
目的探讨小鼠胰岛移植术后服用他克莫司(FK506) 对胰岛移植物生物学功能及再血管化的影响.
方法小鼠胰腺经胶原酶P 灌注消化后, Ficoll-400 不连续密度梯度离心提纯并培养制备供体胰岛 …

[引用][C] 成人胰岛分离纯化技术

程颖, 石蕊, 李桂臣, 吴刚, 刘树荣, 孟一曼, 赵宁… - 中华外科杂志, 2009

[引用][C] 供体胰腺保存方法的改进

董维平, 蔡锦全, 谭建明, 王煜非, 王鉴波, 彭永德 - 中华细胞与干细胞杂志: 电子版, 2011

自家膵島移植の現況

後藤昌史 - 日本消化器病学会雑誌, 2018 - jstage.jst.go.jp
抄録 自家膵島移植は, 膵全摘にともない発症が不可避である糖尿病を免疫抑制剤を用いずに防ぐ
ことができる, 究極の低侵襲再生医療である. 膵外分泌のみ病態を有し内分泌は保たれている慢性 …

(Secondary Publication) Tacrolimus が移植膵島の血管再構築へ及ぼす影響

西村隆一, 西岡翔, 藤澤生麿, 珠玖仁, 島田美貴… - 移植, 2014 - jstage.jst.go.jp
[Objective] Immunosuppressive drugs could be crucial factors for a poor outcome after islet
allotransplantation. Unlike rapamycin, the effects of tacrolimus, the current standard …

[PDF][PDF] タクロリムスが移植膵島の血管新生へ及ぼす影響に関する研究

西村隆一 - 2012 - core.ac.uk
1. 要約膵島移植は, 重症 1 型糖尿病に対する治療法として既に臨床応用が開始されている.
この新しい細胞移植療法は, 従来行なわれてきた膵臓移植と比べ, 安全・簡便・低侵襲などの利点を …