Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …

Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to
invading pathogens and internal changes to cellular homeostasis. Cancer is a stage of …

Although inflammation is a vital defence response to infection, if left uncontrolled, it can lead
to pathology. Macrophages are critical players both in driving the inflammatory response …

Extracellular vesicles (EVs) encompass a diverse set of membrane-derived particles
released from cells and are found in numerous biological matrices and the extracellular …

Breast cancer is one of the leading causes of cancer-related death in women. Currently, the
treatment of breast cancer is limited by the lack of effectively targeted therapy and patients …

Anticancer drug resistance is a significant impediment in current cancer treatment.
Extracellular vesicles (EVs) derived from cancer cells were recently acknowledged as a …

Eukaryotic cells, including cancer cells, secrete highly heterogeneous populations of
extracellular vesicles (EVs). EVs could have different subcellular origin, composition and …

Extracellular vesicles (EVs) are particles released from cells, and their lipid bilayer
membrane encloses large amounts of bioactive molecules that endow EVs with intercellular …

There is still a need for an efficient method for the isolation of extracellular vesicles (EVs)
from human blood that provides a reliable yield with acceptable purity. Blood is a source of …

Filaggrin (FLG) protein is indispensable for multiple aspects of the epidermal barrier function
but its accumulation in a monomeric filaggrin form may initiate premature keratinocytes …