[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal

R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

Role of RAGE in Alzheimer's disease

Z Cai, N Liu, C Wang, B Qin, Y Zhou, M Xiao… - Cellular and molecular …, 2016 - Springer
Receptor for advanced glycation end products (RAGE) is a receptor of the immunoglobulin
super family that plays various important roles under physiological and pathological …

[HTML][HTML] Heterogeneity in Alzheimer's disease diagnosis and progression rates: implications for therapeutic trials

R Duara, W Barker - Neurotherapeutics, 2023 - Elsevier
The clinical presentation and the pathological processes underlying Alzheimer's disease
(AD) can be very heterogeneous in severity, location, and composition including the amount …

Insulin resistance as the molecular link between diabetes and Alzheimer's disease

MMI Abdalla - World Journal of Diabetes, 2024 - pmc.ncbi.nlm.nih.gov
Diabetes mellitus (DM) and Alzheimer's disease (AD) are two major health concerns that
have seen a rising prevalence worldwide. Recent studies have indicated a possible link …

The blood brain barrier in Alzheimer's disease

A Chakraborty, NM De Wit, WM Van Der Flier… - Vascular …, 2017 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people
worldwide. One of the prominent causative factors of AD pathogenesis is cerebral vascular …

3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling

X Li, JC Brooks, J Hu, KI Ford, CJ Easley - Lab on a Chip, 2017 - pubs.rsc.org
A fully automated, 16-channel microfluidic input/output multiplexer (μMUX) has been
developed for interfacing to primary cells and to improve understanding of the dynamics of …

Hidden heterogeneity in Alzheimer's disease: insights from genetic association studies and other analyses

AI Yashin, F Fang, M Kovtun, D Wu, M Duan… - Experimental …, 2018 - Elsevier
Despite evident success in clarifying many important features of Alzheimer's disease (AD)
the efficient methods of its prevention and treatment are not yet available. The reasons are …

Forxiga (dapagliflozin): Plausible role in the treatment of diabetes‐associated neurological disorders

S Shaikh, SMD Rizvi, S Shakil, S Riyaz… - Biotechnology and …, 2016 - Wiley Online Library
Numerous clinical and epidemiological studies have provided direct evidence to strengthen
the link between type 2 diabetes (T2D) and Alzheimer's disease (AD). The possibility that …

SIRT1 as a therapeutic target for Alzheimer's disease

SY Wong, BL Tang - Reviews in the Neurosciences, 2016 - degruyter.com
Alzheimer's disease (AD) is the most prevalent cause of dementia in the aging population
worldwide. SIRT1 deacetylation of histones and transcription factors impinge on multiple …

Murburn concept and murzymes in 2023: Celebrating 25th year of pursuit

KM Manoj - Biomedical Reviews, 2022 - journals.mu-varna.bg
Murburn concept (from “mured burning”; signifies that redox processes involving diffusible
reactive species form indispensable facets of governing key metabolic/physiological facets …