Importance Potentially malignant disorders of the oral cavity (OPMD) are a heterogeneous
group of lesions associated with a variable risk of malignant transformation (MT) to invasive …

Head and neck cancers represent the sixth most common cancer worldwide, with
approximately 630,000 new patients diagnosed annually resulting in more than 350,000 …

The aim of this systematic review was to ascertain the malignant transformation rate of oral
leukoplakia and the associated risk factors. Method Published literature was searched …

Background Oral leukoplakia is a relatively common oral lesion that, in a small proportion of
people, precedes the development of oral cancer. Most leukoplakias are asymptomatic; …

The concept of a two-step process of cancer development in the oral mucosa, ie., the initial
presence of a precursor subsequently developing into cancer, is well-established. Oral …

Background. The aim of this study was to inform an evidence‐based management policy for
oral dysplastic lesions. Methods. Systematic review was performed with meta‐analysis …

The purpose of the present retrospective study was to learn the long-term outcome of oral
premalignant lesions, leukoplakia and erythroplakia, with or without surgical intervention …

This study was aimed at estimating the pooled global leukoplakia prevalence using both
well-designed studies, which were too few to be representative of the world situation, and …

Patients with oral potentially malignant disorders (OPMDs), including oral leukoplakia and
erythroplakia, proliferative verrucous leukoplakia, oral submucous fibrosis, and oral lichen …

Five percent of all tumors occur in the head and neck, and approximately half of those occur
specifically in the oral cavity. Of the 615,000 new cases of oral cavity tumors reported …