The aging GABAergic system and its nutritional support

DJ Mills - Journal of nutrition and metabolism, 2021 - Wiley Online Library
Aging is associated with a decline in hormones and an associated decline in GABAergic
function and calcium and ion current dysregulation. Neurosteroid hormones act as direct …

β-cell replenishment: Possible curative approaches for diabetes mellitus

N Rathwa, R Patel, SP Palit, N Parmar, S Rana… - Nutrition, Metabolism …, 2020 - Elsevier
Aims Diabetes mellitus (DM) is a disorder of heterogeneous etiology marked by persistent
hyperglycemia. Exogenous insulin is the only treatment for type 1 diabetes (T1D). Islet …

Calorie restriction potentiates the therapeutic potential of GABA in managing type 2 diabetes in a mouse model

N Rathwa, N Parmar, SP Palit, R Patel, RS Bhaskaran… - Life Sciences, 2022 - Elsevier
Dysfunctional adipocytes/β-cells advance type 2 diabetes (T2D). Calorie restriction (CR)
improves insulin sensitivity and fasting blood glucose (FBG) levels, while γ-aminobutyric …

Calorie Restriction in combination with GABA: improved glycaemic control in type 2 diabetes mouse model

N Rathwa, N Parmar, SP Palit, R Patel, RS Bhaskaran… - bioRxiv, 2021 - biorxiv.org
Aim Dysfunctional adipocytes and β-cells are crucial in the advancement of obesity-induced
type 2 diabetes (T2D). Calorie restriction (CR) improves insulin sensitivity and fasting blood …