Recent investigations on the non-protein-coding transcriptome of human cells have
revealed previously hidden layers of gene regulation relying on regulatory non-protein …

Early detection of cancers and their precise subtyping are essential to patient stratification
and effective cancer management. Data-driven identification of expression biomarkers …

TarBase is a reference database dedicated to produce, curate and deliver high quality
experimentally-supported microRNA (miRNA) targets on protein-coding transcripts. In its …

DIANA-microT-CDS is a state-of-the-art miRNA target prediction algorithm catering the
scientific community since 2009. It is one of the first algorithms to predict miRNA binding …

Background Studies have suggested that many down-regulated miRNAs identified in the
brain tissue or serum of Alzheimer's disease (AD) patients were involved in the formation of …

Summary Inverted Alu repeats (IRAlus) are abundantly found in the transcriptome,
especially in introns and 3′ untranslated regions (UTRs). Yet, the biological significance of …

A significant fraction of mature miRNA transcripts carries sequence and/or length variations,
termed isomiRs. IsomiRs are differentially abundant in cell types, tissues, body fluids or …

MiRNAs represent a non-coding RNA class that regulate gene expression and pathways.
While miRNAs are evolutionary conserved most data stems from Homo sapiens and Mus …

Transcription termination is a crucial step in the production of conforming mRNAs and
functional proteins. Under cellular stress conditions, the transcription machinery fails to …

Abstract Coronavirus disease-2019 (COVID-19) can be asymptomatic or lead to a wide
symptom spectrum, including multi-organ damage and death. Here, we explored the …