During animal development, cell-fate-specific changes in gene expression can modify the
material properties of a tissue and drive tissue morphogenesis. While mechanistic insights …

Mitotic cell divisions increase cell number while faithfully distributing the replicated genome
at each division. The Caenorhabditis elegans embryo is a powerful model for eukaryotic cell …

Long ignored as a vestigial remnant of cytokinesis, the mammalian midbody (MB) is
released post-abscission inside large extracellular vesicles called MB remnants (MBRs) …

Many developmental processes break left–right (LR) symmetry with a consistent
handedness. LR asymmetry emerges early in development, and in many species the …

Abscission, the final stage of cell division, requires well-orchestrated changes in endocytic
trafficking, microtubule severing, actin clearance, and the physical sealing of the daughter …

This review accompanies a 2016 SFN mini-symposium presenting examples of current
studies that address a central question: How do neural stem cells (NSCs) divide in different …

The midbody remnant (MBR) that is generated after cytokinetic abscission has recently
attracted a lot of attention, because it might have crucial consequences for cell differentiation …

Primary cilia are solitary, microtubule-based protrusions of the cell surface that play
fundamental roles as photosensors, mechanosensors and biochemical sensors. Primary …

Despite the progress made in selective plane illumination microscopy, high-resolution 3D
live imaging of multicellular specimens remains challenging. Tiling light-sheet selective …

The cell cortex is essential to maintain animal cell shape, and contractile forces generated
within it by nonmuscle myosin II (NMY-2) drive cellular morphogenetic processes such as …