The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

The transition between epithelial and mesenchymal phenotype is emerging as a key
determinant of tumor cell invasion and metastasis. It is a plastic process in which epithelial …

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant
free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis …

Amino acid metabolism plays important roles in tumor biology and tumor therapy.
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …

Cancer cells have the plasticity to adjust their metabolic phenotypes for survival and
metastasis. A developmental programme known as epithelial-to-mesenchymal transition …

Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial
cells undergo a reversible phenotype switch via the loss of adhesion capacity and …

Targeted therapies against cancer have improved both survival and quality of life of patients.
However, metabolic rewiring evokes cellular mechanisms that reduce therapeutic …

Introduction Coronavirus disease 2019 is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which enters host cells through the cell …

Recent studies have identified pleiotropic roles of methyltransferase-like 3 (METTL3) in
tumor progression. However, the roles of METTL3 in esophageal squamous cell carcinoma …

Cancer cells undergo transient EMT and MET phenomena or vice versa, along with the
parallel interplay of various markers, often correlated as the determining factor in decoding …