Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the coronavirus
disease 2019 (COVID-19), has provoked more than six million deaths worldwide and …

The global burden of respiratory diseases is very high and still on the rise, prompting the
need for accurate models for basic and translational research. Several model systems are …

Human respiratory viruses induce a wide breadth of disease phenotypes and outcomes of
varying severity. Innovative models that recapitulate the human respiratory tract are needed …

The human respiratory system, consisting of the airway and alveoli, is one of the most
complex organs directly interfaced with the external environment. The diverse epithelial cells …

Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …

Infectious diseases worldwide affect human health and have important societal impacts. A
better understanding of infectious diseases is urgently needed. In vitro and in vivo infection …

The field of precision medicine allows for tailor-made treatments specific to a patient and
thereby improve the efficiency and accuracy of disease prevention, diagnosis, and treatment …

As SARS-CoV-2 continues to spread worldwide, tractable primary airway cell models that
recapitulate the cell-intrinsic response to arising viral variants are needed. Here we describe …

Morbidity and mortality from influenza are associated with high levels of systemic
inflammation. Endothelial cells play a key role in systemic inflammatory responses during …