The gastric mucosal immune system is a unique immune organ independent of systemic
immunity that not only maintains nutrient absorption but also plays a role in resisting the …

Recent studies have advanced our understanding of the pathophysiology of autoimmune
gastritis, particularly its molecular aspects. The most noteworthy recent advancement lies in …

Autoimmune metaplastic atrophic gastritis (AMAG) is associated with an increased risk of
gastric neoplasms. This study aimed to systematically analyze the incidence rate of gastric …

Simple Summary Helicobacter pylori infection represents the major cause of gastric cancer,
and is a type I carcinogen for distal gastric cancer. Gastric oncogenesis is a multi-step …

The effects of specific cytokines produced by T cell subsets (such as Th1, Th2, and newly
discovered Th17, Treg, Tfh, or Th22) are diverse, depending on interactions with other …

The role of autoimmunity in the pathogenesis of gastric cancer remains controversial. We
studied antiparietal cell antibody (anti-PCA) and anti-intrinsic factor antibody (anti-IFA) levels …

Autoimmune gastritis (AIG) and pernicious anemia (PA) are two gastroenterological
conditions closely related and they recognize the same underlying pathophysiological …

Autoimmune gastritis (AIG) is an autoimmune disorder characterized by the destruction of
gastric parietal cells and atrophy of the oxyntic mucosa which induces intrinsic factor …

Cytokines, which are important to the tumor microenvironment (TME), play critical roles in
tumor development, metastasis, and immune responses. Interleukin-17 (IL-17) has emerged …

Parietal cell autoantibodies (PCAs), which recognize the enzyme H+/K+-ATPase as a target,
are considered to be a diagnostic marker of autoimmune gastritis and pernicious anemia; …