Bacterial DNA excision repair pathways

KJ Wozniak, LA Simmons - Nature Reviews Microbiology, 2022 - nature.com
Bacteria are continuously exposed to numerous endogenous and exogenous DNA-
damaging agents. To maintain genome integrity and ensure cell survival, bacteria have …

Impacts of UV radiation on Bacillus biocontrol agents and their resistance mechanisms

AL Idris, W Li, F Huang, F Lin, X Guan… - World Journal of …, 2024 - Springer
Bacillus biocontrol agent (s) BCA (s) such as Bacillus cereus, Bacillus thuringiensis and
Bacillus subtilis have been widely applied to control insects' pests of plants and pathogenic …

Bacillus subtilis Spore Resistance to Simulated Mars Surface Conditions

M Cortesão, FM Fuchs, FM Commichau… - Frontiers in …, 2019 - frontiersin.org
In a Mars exploration scenario, knowing if and how highly resistant Bacillus subtilis spores
would survive on the Martian surface is crucial to design planetary protection measures and …

An underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis

S Million-Weaver, AN Samadpour… - Proceedings of the …, 2015 - National Acad Sciences
We previously reported that lagging-strand genes accumulate mutations faster than those
encoded on the leading strand in Bacillus subtilis. Although we proposed that orientation …

Resistance of Bacillus subtilis spore DNA to lethal ionizing radiation damage relies primarily on spore core components and DNA repair, with minor effects of oxygen …

R Moeller, M Raguse, G Reitz, R Okayasu… - Applied and …, 2014 - Am Soc Microbiol
The roles of various core components, including α/β/γ-type small acid-soluble spore proteins
(SASP), dipicolinic acid (DPA), core water content, and DNA repair by apurinic/apyrimidinic …

Role of DNA repair and protective components in Bacillus subtilis spore resistance to inactivation by 400-nm-wavelength blue light

B Djouiai, JE Thwaite, TR Laws… - Applied and …, 2018 - Am Soc Microbiol
The high intrinsic decontamination resistance of Firmicutes spores is important medically
(disease) and commercially (food spoilage). Effective methods of spore eradication would …

New insights into the structures and interactions of bacterial Y-family DNA polymerases

K Timinskas, Č Venclovas - Nucleic acids research, 2019 - academic.oup.com
Bacterial Y-family DNA polymerases are usually classified into DinB (Pol IV), UmuC (the
catalytic subunit of Pol V) and ImuB, a catalytically dead essential component of the ImuA …

Bacillus subtilis stress-associated mutagenesis and developmental DNA repair

M Pedraza-Reyes, K Abundiz-Yañez… - Microbiology and …, 2024 - Am Soc Microbiol
The metabolic conditions that prevail during bacterial growth have evolved with the faithful
operation of repair systems that recognize and eliminate DNA lesions caused by …

Transcriptomic Responses of Germinating Bacillus subtilis Spores Exposed to 1.5 Years of Space and Simulated Martian Conditions on the EXPOSE-E Experiment …

WL Nicholson, R Moeller, the PROTECT Team… - Astrobiology, 2012 - liebertpub.com
Because of their ubiquity and resistance to spacecraft decontamination, bacterial spores are
considered likely potential forward contaminants on robotic missions to Mars. Thus, it is …

Bacillus subtilis DisA helps to circumvent replicative stress during spore revival

M Raguse, R Torres, EM Seco, C Gándara, S Ayora… - DNA repair, 2017 - Elsevier
The mechanisms that allow to circumvent replicative stress, and to resume DNA synthesis
are poorly understood in Bacillus subtilis. To study the role of the diadenylate cyclase DisA …