Alcohol-related liver disease: basic mechanisms and clinical perspectives

SY Liu, IT Tsai, YC Hsu - International journal of molecular sciences, 2021 - mdpi.com
Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …

Blood biomarkers of alcohol use: a scoping review

JC Harris, L Leggio, M Farokhnia - Current addiction reports, 2021 - Springer
Abstract Purpose of Review Understanding whether a person has consumed alcohol or not,
as well as quantitative assessment of alcohol use, are often based on self-reported …

No safe level of alcohol consumption for brain health: observational cohort study of 25,378 UK Biobank participants

A Topiwala, KP Ebmeier, T Maullin-Sapey, TE Nichols - MedRxiv, 2021 - medrxiv.org
Objectives To estimate the relationship between moderate alcohol consumption and brain
health, determining the threshold intake for harm and identifying whether population …

Comparison of the diagnostic value of phosphatidylethanol and carbohydrate‐deficient transferrin as biomarkers of alcohol consumption

A Årving, G Høiseth, T Hilberg, T Trydal… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background The aim of this study was to compare the results of Phosphatidylethanol (PEth)
and carbohydrate‐deficient transferrin (CDT) in blood as biomarkers of alcohol consumption …

A trauma-informed substance use and sexual risk reduction intervention for young South African women: a mixed-methods feasibility study

B Myers, T Carney, FA Browne, WM Wechsberg - BMJ open, 2019 - bmjopen.bmj.com
Objectives Sexual and physical trauma and substance use are intersecting risks for HIV
among young women. This study assesses the feasibility, acceptability and preliminary …

The roles of phosphatidylethanol, ethyl glucuronide, and ethyl sulfate in identifying alcohol consumption among participants in professionals health programs

GM Reisfield, SA Teitelbaum, SO Opie… - Drug testing and …, 2020 - Wiley Online Library
Direct alcohol biomarkers, including urinary ethyl glucuronide (EtG), urinary ethyl sulfate
(EtS), and blood phosphatidylethanol (PEth), are used to monitor alcohol abstinence in …

Set‐up of a population‐based model to verify alcohol abstinence via monitoring of the direct alcohol marker phosphatidylethanol 16: 0/18: 1

K Van Uytfanghe, L Heughebaert, E Abatih… - …, 2022 - Wiley Online Library
Abstract Background and aims Phosphatidylethanol 16: 0/18: 1 (PEth) is a biomarker for
alcohol intake. It has a half‐life of 7.9 days. Chronic alcohol consumption causes high PEth …

Blood phosphatidylethanol concentrations following regular exposure to an alcohol-based mouthwash

GM Reisfield, SA Teitelbaum, JT Jones… - Journal of analytical …, 2021 - academic.oup.com
Direct biomarkers of ethanol are used to monitor individuals who are required to abstain
from ethanol consumption. In recent years, blood phosphatidylethanol (PEth) has gained …

Determination of phosphatidylethanol 16: 0/18: 1 in whole blood by 96‐well supported liquid extraction and UHPLC‐MS/MS

T Berg, E Eliassen, B Jørgenrud… - Journal of clinical …, 2019 - Wiley Online Library
Background Phosphatidylethanols (PE ths) are specific, direct alcohol biomarkers that can
be determined in human blood to distinguish between heavy and social drinking. PE th 16 …

Fully automated determination of phosphatidylethanol 16: 0/18: 1 and 16: 0/18: 2 in dried blood spots

M Luginbühl, S Gaugler… - Journal of analytical …, 2019 - academic.oup.com
Purpose Direct alcohol markers are widely applied during abstinence monitoring, driving
aptitude assessments and workplace drug testing. The most promising direct alcohol marker …