Plant pan-genomes are the new reference
Recent years have seen a surge in plant genome sequencing projects and the comparison
of multiple related individuals. The high degree of genomic variation observed led to the …
of multiple related individuals. The high degree of genomic variation observed led to the …
[HTML][HTML] Applications of multi-omics technologies for crop improvement
Y Yang, MA Saand, L Huang, WB Abdelaal… - Frontiers in Plant …, 2021 - frontiersin.org
Multiple “omics” approaches have emerged as successful technologies for plant systems
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …
[HTML][HTML] The barley pan-genome reveals the hidden legacy of mutation breeding
M Jayakodi, S Padmarasu, G Haberer, VS Bonthala… - Nature, 2020 - nature.com
Genetic diversity is key to crop improvement. Owing to pervasive genomic structural
variation, a single reference genome assembly cannot capture the full complement of …
variation, a single reference genome assembly cannot capture the full complement of …
[PDF][PDF] Pan-genome of wild and cultivated soybeans
Y Liu, H Du, P Li, Y Shen, H Peng, S Liu, GA Zhou… - Cell, 2020 - cell.com
Soybean is one of the most important vegetable oil and protein feed crops. To capture the
entire genomic diversity, it is needed to construct a complete high-quality pan-genome from …
entire genomic diversity, it is needed to construct a complete high-quality pan-genome from …
[HTML][HTML] Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …
first-line azole antifungal drugs. However, despite its clinical importance, little is known …
[HTML][HTML] Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics
Complete and accurate reference genomes and annotations provide fundamental resources
for functional genomics and crop breeding. Here we report a de novo assembly and …
for functional genomics and crop breeding. Here we report a de novo assembly and …
[HTML][HTML] Eight high-quality genomes reveal pan-genome architecture and ecotype differentiation of Brassica napus
JM Song, Z Guan, J Hu, C Guo, Z Yang, S Wang, D Liu… - Nature Plants, 2020 - nature.com
Rapeseed (Brassica napus) is the second most important oilseed crop in the world but the
genetic diversity underlying its massive phenotypic variations remains largely unexplored …
genetic diversity underlying its massive phenotypic variations remains largely unexplored …
[HTML][HTML] The Human Pangenome Project: a global resource to map genomic diversity
The human reference genome is the most widely used resource in human genetics and is
due for a major update. Its current structure is a linear composite of merged haplotypes from …
due for a major update. Its current structure is a linear composite of merged haplotypes from …
[HTML][HTML] Genome evolution across 1,011 Saccharomyces cerevisiae isolates
J Peter, M De Chiara, A Friedrich, JX Yue, D Pflieger… - Nature, 2018 - nature.com
Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …
natural populations. Here we report the whole-genome sequencing and phenotyping of …
[HTML][HTML] A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche
M Zepeda-Rivera, SS Minot, H Bouzek, H Wu… - Nature, 2024 - nature.com
Fusobacterium nucleatum (Fn), a bacterium present in the human oral cavity and rarely
found in the lower gastrointestinal tract of healthy individuals, is enriched in human …
found in the lower gastrointestinal tract of healthy individuals, is enriched in human …