The characteristic maximum lifespan varies enormously across animal species from a few
hours to hundreds of years. This argues that maximum lifespan, and the ageing process that …

Introduction• Bone fracture healing and healing problems• Biomaterial scaffolds and tissue
engineering in bone formation‐Bone tissue engineering‐Biomaterial scaffolds‐Synthetic …

Wound healing is a complex but a fine‐tuned biological process in which human skin has
the ability to regenerate itself following damage. However, in particular conditions such as …

Current treatments for chronic pain, such as inflammatory pain, neuropathic pain, and
cancer pain are insufficient and cause severe side effects. Mounting evidence suggests that …

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors, initially
described as molecular targets for synthetic compounds inducing peroxisome proliferation …

Steroid hormones are known systemic regulators of multiple normal and cancerous tissues;
however, whether or how they impact the fate and function of adult stem cells is unclear. In …

We recently demonstrated a novel effective therapeutic regimen for treating hamster heart
failure based on injection of bone marrow mesenchymal stem cells (MSCs) or MSC …

Mesenchymal stem cell (MSC) therapy is entering a challenging phase after completion of
many preclinical and clinical trials. Among the major hurdles encountered in MSC therapy …

Adult mesenchymal stem cells (MSCs) are being investigated further for their use in stem
cell therapies. However, as they are found in very low numbers in adult tissue, expansion in …

Importance of the field: Mesenchymal stem cells (MSCs) have the greatest potential for use
in cell-based therapy of human heart diseases, especially in myocardial infarcts. The …