Branched-chain amino acids in metabolic signalling and insulin resistance
Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and
indirect effects. Frequently, BCAAs have been reported to mediate antiobesity effects …
indirect effects. Frequently, BCAAs have been reported to mediate antiobesity effects …
Recent progress on branched-chain amino acids in obesity, diabetes, and beyond
MAB Siddik, AC Shin - Endocrinology and Metabolism, 2019 - synapse.koreamed.org
Branched-chain amino acids (BCAAs) are essential amino acids that are not synthesized in
our body; thus, they need to be obtained from food. They have shown to provide many …
our body; thus, they need to be obtained from food. They have shown to provide many …
Metabolomics and proteomics in type 2 diabetes
ZZ Chen, RE Gerszten - Circulation research, 2020 - Am Heart Assoc
The persistent increase in the worldwide burden of type 2 diabetes mellitus (T2D) and the
accompanying rise of its complications, including cardiovascular disease, necessitates our …
accompanying rise of its complications, including cardiovascular disease, necessitates our …
Amino acid catabolism in Alzheimer's disease brain: friend or foe?
JWD Griffin, PC Bradshaw - Oxidative medicine and cellular …, 2017 - Wiley Online Library
There is a dire need to discover new targets for Alzheimer's disease (AD) drug development.
Decreased neuronal glucose metabolism that occurs in AD brain could play a central role in …
Decreased neuronal glucose metabolism that occurs in AD brain could play a central role in …
[HTML][HTML] Leucine metabolism in T cell activation: mTOR signaling and beyond
EA Ananieva, JD Powell, SM Hutson - Advances in nutrition, 2016 - Elsevier
In connection with the increasing interest in metabolic regulation of the immune response,
this review discusses current advances in understanding the role of leucine and leucine …
this review discusses current advances in understanding the role of leucine and leucine …
Branched-chain amino acids are linked with Alzheimer's disease-related pathology and cognitive deficits
MAB Siddik, CA Mullins, A Kramer, H Shah… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with a complex
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …
Circulating metabolite homeostasis achieved through mass action
X Li, S Hui, ET Mirek, WO Jonsson, TG Anthony… - Nature …, 2022 - nature.com
Homeostasis maintains serum metabolites within physiological ranges. For glucose, this
requires insulin, which suppresses glucose production while accelerating its consumption …
requires insulin, which suppresses glucose production while accelerating its consumption …
[HTML][HTML] Amino acids in the regulation of aging and aging-related diseases
CA Canfield, PC Bradshaw - Translational Medicine of Aging, 2019 - Elsevier
Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …
roles. The mechanisms through which altered levels of many amino acids are sensed and …
Branched-chain amino acids as biomarkers in diabetes
P Giesbertz, H Daniel - Current Opinion in Clinical Nutrition & …, 2016 - journals.lww.com
Branched-chain amino acids as biomarkers in diabetes : Current Opinion in Clinical Nutrition &
Metabolic Care Branched-chain amino acids as biomarkers in diabetes : Current Opinion in …
Metabolic Care Branched-chain amino acids as biomarkers in diabetes : Current Opinion in …
Branched-chain amino acid metabolism: from rare Mendelian diseases to more common disorders
LC Burrage, SCS Nagamani… - Human molecular …, 2014 - academic.oup.com
Branched-chain amino acid (BCAA) metabolism plays a central role in the pathophysiology
of both rare inborn errors of metabolism and the more common multifactorial diseases …
of both rare inborn errors of metabolism and the more common multifactorial diseases …