Branched-chain amino acids (BCAAs) are important nutrient signals that have direct and
indirect effects. Frequently, BCAAs have been reported to mediate antiobesity effects …

Branched-chain amino acids (BCAAs) are essential amino acids that are not synthesized in
our body; thus, they need to be obtained from food. They have shown to provide many …

The persistent increase in the worldwide burden of type 2 diabetes mellitus (T2D) and the
accompanying rise of its complications, including cardiovascular disease, necessitates our …

There is a dire need to discover new targets for Alzheimer's disease (AD) drug development.
Decreased neuronal glucose metabolism that occurs in AD brain could play a central role in …

In connection with the increasing interest in metabolic regulation of the immune response,
this review discusses current advances in understanding the role of leucine and leucine …

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with a complex
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …

Homeostasis maintains serum metabolites within physiological ranges. For glucose, this
requires insulin, which suppresses glucose production while accelerating its consumption …

Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …

Branched-chain amino acids as biomarkers in diabetes : Current Opinion in Clinical Nutrition &
Metabolic Care Branched-chain amino acids as biomarkers in diabetes : Current Opinion in …

Branched-chain amino acid (BCAA) metabolism plays a central role in the pathophysiology
of both rare inborn errors of metabolism and the more common multifactorial diseases …