Cancer is a group of cells that malignantly grow and proliferate uncontrollably. At present,
treatment modes for cancer mainly comprise surgery, chemotherapy, radiotherapy …

In this review, we discuss the major histocompatibility complex (MHC) class II transactivator
(CIITA), which is the master regulator of MHC class II gene expression. CIITA is the founding …

Purpose: Immunotherapy for hepatocellular carcinoma (HCC) shows considerable promise
in improving clinical outcomes. HepaVac-101 represents a single-arm, first-in-human phase …

It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …

Human nucleotide-binding oligomerization domain (NOD)-like receptors (NLR) include a
large family of proteins that have important functions in basic physio-pathological processes …

Previous studies suggested that patients with comorbidities including cancer had a higher
risk of mortality or developing more severe forms of COVID-19. The interaction of cancer and …

Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …

Human T-cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell
leukemia (ATL), an aggressive CD4+/CD25+ T-cell malignancy and of a severe …

Unresolved inflammation is a pathological consequence of persistent inflammatory stimulus
and perturbation in regulatory mechanisms. It increases the risk of tumour development and …

Many members of the nucleotide-binding and oligomerization domain (NACHT)-and leucine-
rich-repeat-containing protein (NLR) family play crucial roles in pathogen recognition and …