Lung injury in neonates: causes, strategies for prevention, and long-term consequences

RH Clark, DR Gerstmann, AH Jobe, ST Moffitt… - The Journal of …, 2001 - jpeds.com
ARDS Acute respiratory distress syndrome BPD Bronchopulmonary dysplasia CPAP
Continuous positive airway pressure EEP End-expiratory pressure FIO2 Fraction of inspired …

Lung function tests in neonates and infants with chronic lung disease: global and regional ventilation inhomogeneity

JJ Pillow, I Frerichs, J Stocks - Pediatric pulmonology, 2006 - Wiley Online Library
This review considers measurement of global and regional ventilation inhomogeneity (VI) in
infants and young children with acute neonatal respiratory disorders and chronic lung …

Alveolar recruitment promotes homogeneous surfactant distribution in a piglet model of lung injury

MF Krause, C Jäkel, J Haberstroh… - Pediatric …, 2001 - nature.com
Uneven distribution of exogenous surfactant contributes to a poor clinical response in
animal models of respiratory distress syndrome. Alveolar recruitment at the time of surfactant …

An official American Thoracic Society/European Respiratory Society workshop report: evaluation of respiratory mechanics and function in the pediatric and neonatal …

S Peterson-Carmichael, PC Seddon… - Annals of the …, 2016 - atsjournals.org
Ready access to physiologic measures, including respiratory mechanics, lung volumes, and
ventilation/perfusion inhomogeneity, could optimize the clinical management of the critically …

Monitoring of lung volume recruitment and derecruitment using oscillatory mechanics during high-frequency oscillatory ventilation in the preterm lamb

JJ Pillow, PD Sly, Z Hantos - Pediatric Critical Care Medicine, 2004 - journals.lww.com
Objectives To determine whether the low-frequency forced oscillation technique (LFOT) can
track changes in lung mechanics resulting from prophylactic intratracheal surfactant and a …

Current surfactant use in premature infants

GK Suresh, RF Soll - Clinics in perinatology, 2001 - perinatology.theclinics.com
The development of exogenous surfactant therapy was a significant and historic advance in
neonatal intensive care. Work by pioneers in the field of surfactant research described the …

[HTML][HTML] Como minimizar a lesão pulmonar no prematuro extremo: propostas

C Suguihara, AC Lessa - Jornal de Pediatria, 2005 - SciELO Brasil
OBJETIVO: Apresentar uma revisão das principais causas da nova displasia
broncopulmonar e as estratégias utilizadas para diminuir sua incidência nos prematuros …

Randomized controlled trial of volume‐targeted synchronized ventilation and conventional intermittent mandatory ventilation following initial exogenous surfactant …

JD Mrozek, EM Bendel‐Stenzel, PA Meyers… - Pediatric …, 2000 - Wiley Online Library
We set out to evaluate the impact of volume‐targeted synchronized ventilation and
conventional intermittent mandatory ventilation (IMV) on the early physiologic response to …

A comparison of the outcomes of neonates treated with two different natural surfactants

RH Clark, RL Auten, J Peabody - The Journal of pediatrics, 2001 - Elsevier
Objective: Our purpose was to determine whether there exists a mortality difference between
neonates treated with Infasurf (surfactant A [SA], ONY, Inc, Amherst, NY) and Survanta …

The lung clearance index in young infants: impact of tidal volume and dead space

G Schmalisch, S Wilitzki, C Bührer… - Physiological …, 2015 - iopscience.iop.org
Lung clearance index (LCI), measured by multiple breath washout (MBW), is one of the most
frequently used measures of ventilation inhomogeneity. This study was designed to …