That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …

Recruitment and activation of monocytes and macrophages are essential for clearance of
malaria infection, but these have also been associated with adverse clinical outcomes. In …

Phagocytosis can be induced via the engagement of Fcγ receptors by antibody-opsonized
material. Furthermore, the efficiency of antibody-induced effector functions has been shown …

Naturally acquired humoral immunity to the malarial parasite Plasmodium falciparum can
protect against disease, although the precise mechanisms remain unclear. Although …

Using genome-wide expression profiles from persons either experimentally challenged with
malaria-infected mosquitoes or naturally infected with Plasmodium falciparum malaria, we …

Monocytes are innate immune cells essential for host protection against malaria. Upon
activation, monocytes function to help reduce parasite burden through phagocytosis …

Ab-mediated rejection (AMR) of solid organ transplants is characterized by intragraft
macrophages. It is incompletely understood how donor-specific Ab binding to graft …

Background The development of protective immunity against malaria is slow and to be
maintained, it requires exposure to multiple antigenic variants of malaria parasites and age …

Background: Increasing evidence implicates involvement of the innate immune system in the
initiation and progression of Parkinson's disease (PD). Monocytes and monocyte-derived …

Plasmodium falciparum malaria is a major global health problem, responsible for up to 1
million deaths each year. Major efforts have been made to develop an effective vaccine …