Recent advances in biomimetic nanodelivery systems: new brain-targeting strategies

J Liao, L Fan, Y Li, QQ Xu, LY Xiong, SS Zhang… - Journal of Controlled …, 2023 - Elsevier
In recent years, brain diseases have seriously threatened human health due to their high
morbidity and mortality. Achieving efficient drug delivery to provide satisfactory therapeutic …

The landscape of biomimetic nanovesicles in brain diseases

Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …

Cell membrane-based biomimetic vehicles for effective central nervous system target delivery: Insights and challenges

H Wu, T Zhang, N Li, J Gao - Journal of Controlled Release, 2023 - Elsevier
Central nervous system (CNS) disorders, including brain tumor, ischemic stroke, Alzheimer's
disease, and Parkinson's disease, threaten human health. And the existence of the blood …

Are therapies that target α-synuclein effective at halting Parkinson's disease progression? A systematic review

AT Rodger, M ALNasser, WG Carter - International Journal of Molecular …, 2023 - mdpi.com
There are currently no pharmacological treatments available that completely halt or reverse
the progression of Parkinson's Disease (PD). Hence, there is an unmet need for …

[HTML][HTML] Bio-clickable, small extracellular vesicles-COCKTAIL therapy for ischemic stroke

K Haroon, H Ruan, H Zheng, S Wu, Z Liu, X Shi… - Journal of Controlled …, 2023 - Elsevier
Delivering large therapeutic molecules via the blood-brain barrier to treat ischemic stroke
remains challenging. NR2B9c is a potent neuroprotective peptide but it's safe and targeted …

In situ fabrication of co-coordinated TCPP-Cur donor-acceptor-type covalent organic framework-like photocatalytic hydrogel for rapid therapy of bacteria-infected …

P Li, B Li, C Wang, X Zhao, Y Zheng, S Wu… - Composites Part B …, 2023 - Elsevier
Pathogenic bacterial infection and the presence of drug-resistant bacteria have been
threatening the health of human. Phototherapy has attracted increasing attention for treating …

Revolutionizing neurocare: biomimetic nanodelivery via cell membranes

J Liao, L Gong, Q Xu, J Wang, Y Yang… - Advanced …, 2024 - Wiley Online Library
Brain disorders represent a significant challenge in medical science due to the formidable
blood–brain barrier (BBB), which severely limits the penetration of conventional …

Cell membrane-based nanomaterials for therapeutics of neurodegenerative diseases

PT Nguyen-Thi, TT Nguyen, HL Phan, TT Ho… - Neurochemistry …, 2023 - Elsevier
Central nervous system (CNS) diseases such as Alzheimer's disease (AD), Parkinson's
disease (PD), glioblastoma (GBM), and peripheral nerve injury have been documented as …

Engineered exosomes mediated targeted delivery of neuroprotective peptide NR2B9c for the treatment of traumatic brain injury

K Haroon, H Zheng, S Wu, Z Liu, Y Tang… - International Journal of …, 2024 - Elsevier
Neuroprotection is one of the core treatment strategies for brain injuries including traumatic
brain injury (TBI). NR2B9c is a promising neuroprotective peptide but its clinical translation …

Brain‐Targeted Black Phosphorus‐Based Nanotherapeutic Platform for Enhanced Hypericin Delivery in Depression

H Tan, K Cao, Y Zhao, J Zhong, D Deng, B Pan… - Small, 2024 - Wiley Online Library
Depression is a significant global health concern that remains inadequately treated due to
the limited effectiveness of conventional drug therapies. One potential therapeutic agent …