[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Secondary osteoporosis

PR Ebeling, HH Nguyen, J Aleksova… - Endocrine …, 2022 - academic.oup.com
Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

The multifunctional role of herbal products in the management of diabetes and obesity: a comprehensive review

MM Rahman, MR Islam, S Shohag, ME Hossain… - Molecules, 2022 - mdpi.com
Obesity and diabetes are the most demanding health problems today, and their prevalence,
as well as comorbidities, is on the rise all over the world. As time goes on, both are …

Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Obesity, bioactive lipids, and adipose tissue inflammation in insulin resistance

I Kojta, M Chacińska, A Błachnio-Zabielska - Nutrients, 2020 - mdpi.com
Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes.
The exact mechanism by which adipose tissue induces insulin resistance is still unclear. It …

[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus

MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Branched-chain amino acids: catabolism in skeletal muscle and implications for muscle and whole-body metabolism

G Mann, S Mora, G Madu, OAJ Adegoke - Frontiers in Physiology, 2021 - frontiersin.org
Branched-chain amino acids (BCAAs) are critical for skeletal muscle and whole-body
anabolism and energy homeostasis. They also serve as signaling molecules, for example …

The effects of inflammation, aging and oxidative stress on the pathogenesis of diabetes mellitus (type 2 diabetes)

M Halim, A Halim - Diabetes & metabolic syndrome: clinical research & …, 2019 - Elsevier
Diabetes mellitus is seen to be prevalent among the different epidemics. The prevalence
rate of the diabetes mellitus is seen to be increasing in different regions of the world. Type 2 …

Mechanisms of diabetes mellitus-induced bone fragility

N Napoli, M Chandran, DD Pierroz… - Nature Reviews …, 2017 - nature.com
The risk of fragility fractures is increased in patients with either type 1 diabetes mellitus
(T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in …

Defining the underlying defect in insulin action in type 2 diabetes

TM Batista, N Haider, CR Kahn - Diabetologia, 2021 - Springer
Insulin resistance is one of the earliest defects in the pathogenesis of type 2 diabetes. Over
the past 50 years, elucidation of the insulin signalling network has provided important …