Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma

KMM Espíndola, RG Ferreira, LEM Narvaez… - Frontiers in …, 2019 - frontiersin.org
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …

Current and future treatment of hepatocellular carcinoma: an updated comprehensive review

S Daher, M Massarwa, AA Benson… - Journal of clinical and …, 2017 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality.
The principal treatment is surgical resection or liver transplantation, depending on whether …

Collagen 1A1 (COL1A1) is a reliable biomarker and putative therapeutic target for hepatocellular carcinogenesis and metastasis

HP Ma, HL Chang, OA Bamodu, VK Yadav, TY Huang… - Cancers, 2019 - mdpi.com
Increasing evidence shows that hepatocellular carcinoma (HCC) is a principal cause of
cancer-related mortality globally, especially among Asian and African populations. Collagen …

[HTML][HTML] Hepatocellular carcinoma: a comprehensive review of biomarkers, clinical aspects, and therapy

NM Tunissiolli, MMU Castanhole-Nunes… - Asian Pacific journal …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a cause of several deaths related to cancer worldwidely.
In early stage, curative treatments such as surgical resection, liver transplant and local …

[HTML][HTML] Metformin in the prevention of hepatocellular carcinoma in diabetic patients: a systematic review

V Cunha, HP Cotrim, R Rocha, K Carvalho… - Annals of hepatology, 2020 - Elsevier
Preventive effect of metformin in hepatocellular carcinoma (HCC) is not entirely clear. We
aimed to evaluate the use of metformin as a protective factor of HCC in diabetic patients.. We …

Exosomes in hepatocellular carcinoma: a new horizon

R Chen, X Xu, Y Tao, Z Qian, Y Yu - Cell Communication and Signaling, 2019 - Springer
Exosomes are a class of extracellular vesicles released by multiple cells types including
tumor cells, with a size range of 30-100 nm and a lipid bilayer membrane. Recently, the role …

Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells

J Zhang, W Shan, T Jin, G Wu, X Xiong, H Jin… - Journal of translational …, 2014 - Springer
Objective We previously confirmed that propofol directly inhibited the viability, proliferation,
and invasiveness of hepatocellular carcinoma cells in vitro. In this study, we investigated the …

Exosomal delivery of TRAIL and miR-335 for the treatment of hepatocellular carcinoma

N Thapa, YJ Chwae, KH Yoo… - International …, 2022 - spandidos-publications.com
Liver cancer is the sixth most prevalent type of cancer worldwide and accounts for the third
most frequent cause of cancer-associated mortality. Conventional anticancer drugs display …

[HTML][HTML] Tumor microenvironment in primary liver tumors: A challenging role of natural killer cells

MA Polidoro, J Mikulak, V Cazzetta, A Lleo… - World journal of …, 2020 - ncbi.nlm.nih.gov
In the last years, several studies have been focused on elucidate the role of tumor
microenvironment (TME) in cancer development and progression. Within TME, cells from …

Phase angle as a severity indicator for liver diseases

AP Pagano, JMF Sicchieri, IL Schiavoni, D Barbeiro… - Nutrition, 2020 - Elsevier
Objective The aim of this study was to evaluate the applicability of phase angle (PhA) as a
severity indicator of chronic liver diseases. Methods We examined the medical records of 54 …