Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Role of oxidative damage in toxicity of particulates

P Møller, NR Jacobsen, JK Folkmann… - Free radical …, 2010 - Taylor & Francis
Particulates are small particles of solid or liquid suspended in liquid or air. In vitro studies
show that particles generate reactive oxygen species, deplete endogenous antioxidants …

Targeting chelatable iron as a therapeutic modality in Parkinson's disease

D Devos, C Moreau, JC Devedjian, J Kluza… - Antioxidants & redox …, 2014 - liebertpub.com
Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …

Cumulative effect of PM2.5 components is larger than the effect of PM2.5 mass on child health in India

E Chaudhary, F George, A Saji, S Dey, S Ghosh… - Nature …, 2023 - nature.com
While studies on ambient fine particulate matter (PM2. 5) exposure effect on child health are
available, the differential effects, if any, of exposure to PM2. 5 species are unexplored in …

Synergistic and antagonistic interactions among the particulate matter components in generating reactive oxygen species based on the dithiothreitol assay

H Yu, J Wei, Y Cheng, K Subedi… - Environmental science & …, 2018 - ACS Publications
We assessed the interactions among the particulate matter (PM) components in generating
the reactive oxygen species (ROS) based on a dithiothreitol (DTT) assay. We started with the …

Fine particulate matter in acute exacerbation of COPD

L Ni, CC Chuang, L Zuo - Frontiers in physiology, 2015 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common airway disorder. In particular,
acute exacerbations of COPD (AECOPD) can significantly reduce pulmonary function. The …

Proinflammatory effects and oxidative stress within human bronchial epithelial cells exposed to atmospheric particulate matter (PM2. 5 and PM> 2.5) collected from …

BF Cachon, S Firmin, A Verdin, L Ayi-Fanou… - Environmental …, 2014 - Elsevier
After particulate matter (PM) collection in Cotonou (Benin), a complete physicochemical
characterization of PM 2.5 and PM> 2.5 was led. Then, their adverse health effects were …

Reducing the burden of anaemia in Indian women of reproductive age with clean-air targets

E Chaudhary, S Dey, S Ghosh, S Sharma… - Nature …, 2022 - nature.com
India has one of the highest (53%) global prevalences of anaemia among women of
reproductive age (WRA, 15–49 years). Long-term exposure to ambient fine particulate …

Air pollution-derived PM2. 5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells

B Leclercq, J Kluza, S Antherieu, J Sotty… - Environmental …, 2018 - Elsevier
In order to clarify whether the mitochondrial dysfunction is closely related to the cell
homeostasis maintenance after particulate matter (PM 2.5) exposure, oxidative …

Pro-inflammatory effects and oxidative stress in lung macrophages and epithelial cells induced by ambient particulate matter

S Michael, M Montag, W Dott - Environmental pollution, 2013 - Elsevier
The objective of this study was to compare the toxicological effects of different source-related
ambient PM10 samples in regard to their chemical composition. In this context we …