Tightly orchestrated programmed cell death (PCD) signalling events occur during normal
neuronal development in a spatially and temporally restricted manner to establish the neural …

Despite decades of intense research, the complex biology of glioblastoma (GBM) is not
completely understood. Progression-free survival and overall survival have remained …

The role of autophagy in cancer onset and progression appears still controversial. On one
hand, autophagy allows cancer cell to survive in unfavorable environmental conditions, on …

Glioma is the most frequent and aggressive type of brain neoplasm, being anaplastic
astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …

Glioblastoma multiforme is the most malignant and aggressive type of brain tumor, with a
mean life expectancy of less than 15 months. This is due in part to the high resistance to …

Lower-grade glioma (LGG) is characterized by genetic and transcriptional heterogeneity,
and a dismal prognosis. Iron metabolism is considered central for glioma tumorigenesis …

ABSTRACT WNT-CTNN1B signaling promotes cancer cell proliferation and stemness.
Furthermore, recent evidence indicates that macroautophagy/autophagy regulates WNT …

Glioblastoma (GBM) is one of the most malignant and aggressive primary brain tumor, with a
mean life expectancy of less than 15 months. The malignant nature of GBM prompts the …

Autophagy is a process essential for cellular energy consumption, survival, and defense
mechanisms. The role of autophagy in several types of human cancers has been explicitly …

Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain
tumor in adults, with a poor median survival of approximately 15 months after diagnosis …