A review on evaluation of technetium-99m labeled radiopharmaceuticals

MU Akbar, MR Ahmad, A Shaheen… - Journal of Radioanalytical …, 2016 - Springer
In the past few years, substantial progress has been made in technetium chemistry,
including the synthesis of a variety of 99m Tc-radiopharmaceuticals. This synthesis can be …

Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection

T Kniess, M Laube, F Wüst, J Pietzsch - Dalton transactions, 2017 - pubs.rsc.org
In nuclear medicine, the detection of inflamed and infected lesions is of growing interest.
Extensive efforts have been made to develop radiopharmaceuticals specific for inflammation …

Processing methods of bionanocomposites

MU Akbar, F Rehman, M Ibrahim, M Barikani… - Bionanocomposites, 2020 - Elsevier
Currently, the scientific community is devoting considerable attention to developing
environment-friendly polymeric materials (bionanocomposite) due to their nontoxic …

Radiolabeling, quality control, and biological characterization of 177Lu‐labeled kanamycin

MU Akbar, TH Bokhari, M Khalid… - Chemical Biology & …, 2017 - Wiley Online Library
Kanamycin is an antibiotic, isolated from Streptomyces kanamyceticus, which is used to treat
serious bacterial infections. The fact that the present radioligand 99mTc‐kanamycin used for …

Synthesis, quality control, and bio‐evaluation of 99mTc‐cyclophosphamide

TH Bokhari, S Roohi, S Hina, MU Akbar… - Chemical Biology & …, 2018 - Wiley Online Library
Cancer is found to be the leading cause of death worldwide characterized by uncontrolled
cell division. Nuclear medicines imaging using radiopharmaceuticals have pronounced …

Development, optimization, and biovalidation of 99mTc–insulin complex

MU Akbar, TH Bokhari, S Roohi, KM Zia… - Russian Journal of …, 2016 - Springer
Human biosynthetic insulin is a polypeptide hormone that plays an important and essential
role in control of the level of carbohydrate, protein, and fat metabolism in the blood. Human …

Preparation, optimization and pharmacological evaluation of 99mTc- 4-hydroxy-3-(2-hydroxy-3-methoxybenzylideneamino) benzoic acid complex: as a novel …

MU Akbar - Molecular biology reports, 2018 - Springer
Schiff base ligands are biologically active compounds in having antimicrobial, antiviral and
antitumor activities etc. In this study, we have synthesized a Schiff base ligand namely 4 …

Radiosynthesis, radiochemical, and biological characterization of 177Lu‐labeled diethylenetriamine penta‐acetic acid

MU Akbar, TH Bokhari, MR Ahmad… - Journal of Cellular …, 2019 - Wiley Online Library
Diethylenetriamine penta‐acetic acid (DTPA), when complexed with a gamma (γ)‐emitter
radioisotope like 99mTc, is used for renal function diagnosis and many other diagnostic …

Curcumin-based bionanocomposites

MU Akbar, KM Zia, MI Malik, M Zahid, RA Khera… - Bionanocomposites, 2020 - Elsevier
Bionanocomposites are becoming popular owing to their matchless characteristics, such as
their recyclability, low cost, and abundance as well as their lower mass to volume ratio. In …