A common feature of pesticides: oxidative stress—the role of oxidative stress in pesticide‐induced toxicity

RO Sule, L Condon, AV Gomes - Oxidative medicine and …, 2022 - Wiley Online Library
Pesticides are important chemicals or biological agents that deter or kill pests. The use of
pesticides has continued to increase as it is still considered the most effective method to …

COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence

A Tsatsakis, D Petrakis, TK Nikolouzakis… - Food and Chemical …, 2020 - Elsevier
Occupational, residential, dietary and environmental exposures to mixtures of synthetic
anthropogenic chemicals after World War II have a strong relationship with the increase of …

Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives

D Tsoukalas, P Fragkiadaki… - Molecular …, 2019 - spandidos-publications.com
Telomere length, a marker of cellular aging, decreases with age and it has been associated
with aging‑related diseases. Environmental factors, including diet and lifestyle factors, affect …

Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases

S Gangemi, E Gofita, C Costa… - International …, 2016 - spandidos-publications.com
Pesticides can exert numerous effects on human health as a consequence of both
environmental and occupational exposures. The available knowledge base suggests that …

Effects of single and combined toxic exposures on the gut microbiome: Current knowledge and future directions

J Tsiaoussis, MN Antoniou, I Koliarakis, R Mesnage… - Toxicology letters, 2019 - Elsevier
Human populations are chronically exposed to mixtures of toxic chemicals. Predicting the
health effects of these mixtures require a large amount of information on the mode of action …

Occupational exposure to pesticides and the incidence of lung cancer in the agricultural health study

MR Bonner, LEB Freeman, JA Hoppin… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Occupational pesticide use is associated with lung cancer in some, but not all,
epidemiologic studies. In the Agricultural Health Study (AHS), we previously reported …

Human exposure to chemical mixtures: challenges for the integration of toxicology with epidemiology data in risk assessment

AF Hernández, AM Tsatsakis - Food and Chemical Toxicology, 2017 - Elsevier
Little is known about the potential adverse effects from longterm exposure to complex
mixtures at low doses, close to health-based reference values. Traditional chemical-specific …

Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasures

V Aroniadou-Anderjaska, JP Apland, TH Figueiredo… - …, 2020 - Elsevier
Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to
nerve agents can cause rapid death. In this review, we summarize the history of nerve agent …

Pesticides and cardiotoxicity. Where do we stand?

N Georgiadis, K Tsarouhas, C Tsitsimpikou… - Toxicology and applied …, 2018 - Elsevier
Cardiovascular diseases are among the most significant causes of mortality in humans.
Pesticides toxicity and risk for human health are controlled at a European level through a …

New challenges in risk assessment of chemicals when simulating real exposure scenarios; simultaneous multi-chemicals' low dose exposure

AM Tsatsakis, AO Docea, C Tsitsimpikou - Food and Chemical Toxicology, 2016 - Elsevier
The general population experiences uncontrolled multi-chemicals exposure from many
different sources at doses around or well below regulatory limits. Therefore, traditional …