Background: Autonomic nervous system (ANS) dysfunction is a putative underlying
mechanism for increased cardiovascular disease risk in individuals with psychiatric …

In this issue of Structure, Holmes et al.(2005) describe elements of an innate defense
mechanism that provides mammals a means to restrict bacterial growth. The host protein …

The treatment of schizophrenia has evolved over the past half century primarily in the
context of antipsychotic drug development. Although there has been significant progress …

As a result of superior efficacy and overall tolerability, atypical antipsychotic drugs have
become the treatment of choice for schizophrenia and related disorders, despite their side …

Obesity and metabolic syndrome, with increased risk of eventual cardiovascular disease
and type II diabetes, are significant problems for patients receiving antipsychotic drugs and …

Background Most antipsychotics are associated with weight gain and other metabolic
complications. Several randomized trials have shown metformin to be effective, but this still …

Atypical antipsychotic drugs offer several notable benefits over typical antipsychotics,
including greater improvement in negative symptoms, cognitive function, prevention of …

These guidelines from the British Association for Psychopharmacology address the scope
and targets of pharmacological treatment for schizophrenia. A consensus meeting, involving …

Antipsychotic drugs can be of great benefit in a range of psychiatric disorders, including
schizophrenia and bipolar disorder, but all are associated with a wide range of potential …

One of the most widely used guides to prescribing psychiatric medications, the Tenth Edition
of Maudsley Prescribing Guidelines returns with fully updated content and new sections on …