The renin-angiotensin system has powerful effects in control of the blood pressure and
sodium homeostasis. These actions are coordinated through integrated actions in the …

Abstract Angiotensin-converting enzyme (ACE)—a zinc-dependent dicarboxypeptidase with
two catalytic domains—plays a major part in blood pressure regulation by converting …

Obesity is a pandemic and a serious global health concern. Obesity is a risk factor for
multiple conditions and contributes to multi-morbidities, resulting in increased health costs …

The importance of host genetics and demography in coronavirus disease 2019 (COVID-19)
is a crucial aspect of infection, prognosis and associated case fatality rate. Individual genetic …

Abstract Angiotensin-converting enzyme 2 (ACE2), discovered as a homologue of ACE, acts
as its physiological counterbalance providing homeostatic regulation of circulating …

The renin-angiotensin system (RAS) conceived as a coordinated hormonal cascade plays
an important role in controlling multiple functions in many organs and is much more complex …

Angiotensin-converting enzyme (ACE) is a zinc-dependent dipeptidyl carboxypeptidase and
is crucial in the renin-angiotensin-aldosterone system (RAAS) but also implicated in immune …

Simple Summary Angiotensin inhibitors are broadly applied in the treatment of renal and
cardiovascular diseases. This review aims to show that these drugs have also been …

For numerous years, the non‑cardiovascular role of the renin‑angiotensin system (RAS) was
underestimated, but recent studies have advanced the understanding of its function in …

Ageing has been associated with comorbidities, systemic low-grade of inflammation, and
immunosenescence. Hypertension is the most common morbidity and anti-hypertensives …