Pharmacological and toxicological properties of Nigella sativa

BH Ali, G Blunden - Phytotherapy Research: An international …, 2003 - Wiley Online Library
The seeds of Nigella sativa Linn.(Ranunculaceae), commonly known as black seed or black
cumin, are used in folk (herbal) medicine all over the world for the treatment and prevention …

Thymoquinone: a promising anti-cancer drug from natural sources

H Gali-Muhtasib, A Roessner… - The international journal …, 2006 - Elsevier
There has been growing interest in naturally occurring compounds with anti-cancer
potential. Black seed is one of the most extensively studied plants. This annual herb grows …

Thymoquinone is a potent superoxide anion scavenger

OA Badary, RA Taha, AM Gamal El-Din… - Drug and chemical …, 2003 - Taylor & Francis
The antioxidant and pro-oxidant effects of thymoquinone (TQ), a natural main constituent of
the volatile oil of Nigella sativa seeds, and a synthetic structurally-related tert …

The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice

MR Mahmoud, HS El-Abhar, S Saleh - Journal of ethnopharmacology, 2002 - Elsevier
It has been reported that Nigella sativa oil possesses anticestode and antinematode actions.
Besides, it produced a hepatoprotective effect in some models of liver toxicity. Therefore, our …

Protective effect of thymoquinone against doxorubicin–induced cardiotoxicity in rats: A possible mechanism of protection

MN Nagi, MA Mansour - Pharmacological research, 2000 - Elsevier
Administration of thymoquinone (10 mg kg− 1day− 1, po) with drinking water starting 5 days
before a single injection of doxorubicin (15 mg kg− 1i. p.) and continuing during the …

The influence of thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats

OA Badary, AB Abdel-Naim, MH Abdel-Wahab… - Toxicology, 2000 - Elsevier
The effect of thymoquinone (TQ), the main constituent of the volatile oil of Nigella sativa
seeds, on the nephropathy and oxidative stress induced by doxorubicin (DOX) in rats was …

Chemical composition and medicinal properties of Nigella sativa Linn.

MA Khan - Inflammopharmacology, 1999 - Springer
The black cumin or Nigella sativa L. seeds have many acclaimed medicinal properties such
as bronchodilatory, hypotensive, antibacterial, antifungal, analgesic, anti-inflammatory and …

Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus

H Hosseinzadeh, S Parvardeh, MN Asl, HR Sadeghnia… - Phytomedicine, 2007 - Elsevier
It has been previously reported that Nigella sativa oil (NSO) and thymoquinone (TQ), active
constituent of N. sativa seeds oil, may prevent oxidative injury in various models. Therefore …

[HTML][HTML] Overview of major classes of plant-derived anticancer drugs

A Amin, H Gali-Muhtasib, M Ocker… - … journal of biomedical …, 2009 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death worldwide. Conventional cancer therapies
cause serious side effects and, at best, merely extend the patient's lifespan by a few years …

Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice

A Ilhan, A Gurel, F Armutcu, S Kamisli, M Iraz - Neuropharmacology, 2005 - Elsevier
Nigella sativa oil (NSO), a herbaceous plant, has been used for thousands of years for
culinary and medical purposes. This study aimed to investigate the anticonvulsant and …