Over the last few decades there has been a huge interest in nanostructured functional
materials and assembly techniques for preparing functional molecular assemblies with …

More than a century ago, it was proposed that mechanical forces could drive tissue
formation. However, only recently with the advent of enabling biophysical and molecular …

The recapitulation of complex microenvironments that regulate cell behavior during
development, disease, and wound healing is key to understanding fundamental biological …

A range of magnesium ions (Mg 2+) used has demonstrated osteogenic tendency in vitro.
Hence, we propose to actualize this concept by designing a new system to precisely control …

Controlling the bulk and surface properties of materials is a real challenge for bioengineers
working in the fields of biomaterials, tissue engineering and biophysics. The layer-by-layer …

MicroRNAs (miRNAs) are a new therapeutic tool that can target multiple genes by inducing
translation repression and target mRNA degradation. Although miRNAs have gained …

The micro/nano hybrid structure is considered to be a biomaterial characteristic to stimulate
osteogenesis by mimicking the three-dimensional structure of the bone matrix. However, the …

Materials science offers a powerful tool to control mesenchymal stem cell (MSC) growth and
differentiation into functional phenotypes. A complex interplay between the extracellular …

Growth factors (GFs) are powerful signaling molecules with the potential to drive
regenerative strategies, including bone repair and vascularization. However, GFs are …

Tissue engineering uses cells, signaling molecules, and/or biomaterials to regenerate
injured or diseased tissues. Ex vivo expanded mesenchymal stem cells (MSC) have long …