[HTML][HTML] LncRNAs: key players and novel insights into diabetes mellitus

X He, C Ou, Y Xiao, Q Han, H Li, S Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Long non-coding RNAs (LncRNAs) are a class of endogenous RNA molecules,
which have a transcribing length of over 200 nt, lack a complete functional open reading …

The emerging roles of the β-secretase BACE1 and the long non-coding RNA BACE1-AS in human diseases: a focus on neurodegenerative diseases and cancer

A Sayad, S Najafi, BM Hussen, ST Abdullah… - Frontiers in Aging …, 2022 - frontiersin.org
The β-Secretase (BACE1) is widely studied to be particularly involved in amyloid deposition,
a process known as the pathogenic pathway in neurodegenerative diseases. Therefore …

Circulating long noncoding RNA HOTAIR is an essential mediator of acute myocardial infarction

L Gao, Y Liu, S Guo, R Yao, L Wu, L Xiao… - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: Acute myocardial infarction (AMI) is one of the leading causes of
death in the world. However, specific diagnostic biomarkers have not been fully determined …

Weighted gene co-expression network analysis identifies critical genes in the development of heart failure after acute myocardial infarction

X Niu, J Zhang, L Zhang, Y Hou, S Pu, A Chu… - Frontiers in …, 2019 - frontiersin.org
Background: The development of heart failure (HF) remains a common complication
following an acute myocardial infarction (AMI), and is associated with substantial adverse …

[HTML][HTML] Circular RNAs promote TRPM3 expression by inhibiting hsa-miR-130a-3p in coronary artery disease patients

RY Pan, P Liu, HT Zhou, WX Sun, J Song, J Shu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
We investigated the differential expression of circular RNAs (circRNAs) in plasma samples
from three coronary artery disease (CAD) patients to identify putative therapeutic targets. We …

[HTML][HTML] Cardiovascular disease-related miRNAs expression: potential role as biomarkers and effects of training exercise

S Ultimo, G Zauli, AM Martelli, M Vitale, JA McCubrey… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) are one of the most important causes of mortality
worldwide, therefore the need of effective preventive strategies is imperative. Aging is …

Construction and analysis of the lncRNA‑miRNA‑mRNA network based on competitive endogenous RNA reveals functional genes in heart failure

G Wang, X Zheng, Y Zheng, R Cao… - Molecular …, 2019 - spandidos-publications.com
Heart failure (HF) is a principal cause of morbidity and mortality worldwide, affecting an
estimated 38 million people. Although significant progress has been made with respect to …

Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization

R Tappu, J Haas, DH Lehmann… - PloS one, 2022 - journals.plos.org
Dilated cardiomyopathy (DCM), a myocardial disease, is heterogeneous and often results in
heart failure and sudden cardiac death. Unavailability of cardiac tissue has hindered the …

The impact of spiritual care education on anxiety in family caregivers of patients with heart failure

M Borji, SR Mousavimoghadam, E Salimi… - Journal of religion and …, 2019 - Springer
Heart failure (HF) has been emerging as a general health problem over recent decades.
Spiritual care is a type of support service provided to patients suffering from HF. Spiritual …

A temporal transcriptome and methylome in human embryonic stem cell-derived cardiomyocytes identifies novel regulators of early cardiac development

K Fu, H Nakano, M Morselli, T Chen, H Pappoe… - Epigenetics, 2018 - Taylor & Francis
Stem cell-based cardiogenesis has become a powerful tool to enhance our understanding
of cardiac development and test novel therapeutics for cardiovascular diseases. However …