Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota

AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome

Y Jin, J Chi, K LoMonaco, A Boon, H Gu - TrAC Trends in Analytical …, 2023 - Elsevier
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …

[HTML][HTML] The role of intestinal microbiota and its metabolites in intestinal and extraintestinal organ injury induced by intestinal ischemia reperfusion injury

F Deng, ZB Lin, QS Sun, Y Min, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Intestinal ischemia/reperfusion (I/R) is a common pathophysiological process in clinical
severe patients, and the effect of intestinal I/R injury on the patient's systemic …

Adverse health effects of emerging contaminants on inflammatory bowel disease

X Chen, S Wang, X Mao, X Xiang, S Ye… - Frontiers in Public …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is becoming increasingly prevalent with the improvement
of people's living standards in recent years, especially in urban areas. The emerging …

Gut microbiota as a potential player in Mn-induced neurotoxicity

AA Tinkov, AC Martins, DS Avila, VA Gritsenko… - Biomolecules, 2021 - mdpi.com
Manganese (Mn) is an essential metal, which at high exposures causes neurotoxic effects
and neurodegeneration. The neurotoxic effects of Mn are mediated by neuroinflammation …

Halogenated antimicrobial agents to combat drug-resistant pathogens

OS Faleye, BR Boya, JH Lee, I Choi, J Lee - Pharmacological Reviews, 2024 - ASPET
Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …

Host-microbiota affects the toxicity of Aflatoxin B1 in Caenorhabditis elegans

B Tang, KS Xue, JS Wang, PL Williams… - Food and Chemical …, 2023 - Elsevier
Aflatoxins are a group of potent fungal metabolites produced by Aspergillus and commonly
contaminate groundnuts and cereal grains. Aflatoxin B 1 (AFB 1), the most potent mycotoxin …

Physical exercise and persistent organic pollutants

C Liu, H sheng Hou - Heliyon, 2023 - cell.com
Exposure to the legacy and emerging persistent organic pollutants (POPs) incessantly has
become an important threat to individual health, which is closely related to …

Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study

LL Xu, QY Zhang, YK Chen, LJ Chen, KK Zhang… - Environmental …, 2022 - Elsevier
Although Polychlorinated biphenyl (PCB) levels are decreased in the environment, the
adverse effects of gestational exposure on the mother and offspring cannot be ignored due …

Agroecological transition: towards a better understanding of the impact of ecology-based farming practices on soil microbial ecotoxicology

ML Vermeire, C Thiour-Mauprivez… - FEMS Microbiology …, 2024 - academic.oup.com
Alternative farming systems have developed since the beginning of industrial agriculture.
Organic, biodynamic, conservation farming, agroecology and permaculture, all share a …