Epstein–Barr virus: more than 50 years old and still providing surprises
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …
discovered. EBV has subsequently been found to be associated with a diverse range of …
Epstein–Barr virus: 40 years on
LS Young, AB Rickinson - Nature Reviews Cancer, 2004 - nature.com
Epstein–Barr virus (EBV) was discovered 40 years ago from examining electron
micrographs of cells cultured from Burkitt's lymphoma, a childhood tumour that is common in …
micrographs of cells cultured from Burkitt's lymphoma, a childhood tumour that is common in …
[HTML][HTML] Epstein-Barr virus and nasopharyngeal carcinoma
LS Young, CW Dawson - Chinese journal of cancer, 2014 - ncbi.nlm.nih.gov
Since its discovery 50 years ago, Epstein-Barr virus (EBV) has been linked to the
development of cancers originating from both lymphoid and epithelial cells. Approximately …
development of cancers originating from both lymphoid and epithelial cells. Approximately …
TSGene: a web resource for tumor suppressor genes
Tumor suppressor genes (TSGs) are guardian genes that play important roles in controlling
cell proliferation processes such as cell-cycle checkpoints and inducing apoptosis …
cell proliferation processes such as cell-cycle checkpoints and inducing apoptosis …
Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive …
CpG island methylation is an important mechanism for inactivating the genes involved in
tumorigenesis. Gastric carcinoma (GC) is one of the tumors that exhibits a high frequency of …
tumorigenesis. Gastric carcinoma (GC) is one of the tumors that exhibits a high frequency of …
Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein–Barr virus
M Kusano, M Toyota, H Suzuki, K Akino, F Aoki… - Cancer, 2006 - Wiley Online Library
BACKGROUND The CpG island methylator phenotype (CIMP), which is characterized by
simultaneous methylation of the CpG islands of multiple genes, has been recognized as one …
simultaneous methylation of the CpG islands of multiple genes, has been recognized as one …
[HTML][HTML] Epstein–Barr virus and carcinogenesis: beyond Burkitt's lymphoma
Subsequent to its discovery over 45 years ago, Epstein–Barr virus (EBV) has been
associated with numerous human carcinomas. Approximately 95% of the world's population …
associated with numerous human carcinomas. Approximately 95% of the world's population …
Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia
T Waki, G Tamura, T Tsuchiya, K Sato… - The American journal of …, 2002 - Elsevier
Silencing of tumor suppressor and tumor-related genes by hypermethylation at promoter
CpG islands is one of the major events in human tumorigenesis. Promoter methylation is …
CpG islands is one of the major events in human tumorigenesis. Promoter methylation is …
Epstein-Barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with Epstein-Barr virus-negative carcinoma
Purpose: EBV has been detected in 2–16% of gastric carcinomas. However, there is little
information available about the gene expression profile of EBV-positive gastric carcinomas …
information available about the gene expression profile of EBV-positive gastric carcinomas …
Epstein-Barr virus infection is common in inflamed gastrointestinal mucosa
JL Ryan, YJ Shen, DR Morgan, LB Thorne… - Digestive diseases and …, 2012 - Springer
Abstract Background and Aims Epstein-Barr virus (EBV) is present in the malignant
epithelial cells of 10% of all gastric adenocarcinomas; however, localization of the virus in …
epithelial cells of 10% of all gastric adenocarcinomas; however, localization of the virus in …