The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

Endogenous glucocorticoids are crucial to various physiological processes, including
metabolism, development and inflammation. Since 1948, synthetic glucocorticoids have …

Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Nutrition plays a critical role in the homeostatic balance, maintenance of health, and
longevity. There is a close link between inflammatory diseases and nutritional health …

Chronic unresolved inflammation plays a causal role in the development of advanced
atherosclerosis, but the mechanisms that prevent resolution in atherosclerosis remain …

The concept that chemokines, cytokines and pro-inflammatory mediators act in a co-
ordinated fashion to drive the initiation of the inflammatory reaction is well understood. The …

Resolution of inflammation is a coordinated and active process aimed at restoration of tissue
integrity and function. This review integrates the key molecular and cellular mechanisms of …

Inflammation is a protective response essential for maintaining human health and for fighting
disease. As an active innate immune reaction to challenge, inflammation gives rise to …

Cancer therapy reduces tumor burden by killing tumor cells, yet it simultaneously creates
tumor cell debris that may stimulate inflammation and tumor growth. Thus, conventional …