Toward multi-targeted platinum and ruthenium drugs—a new paradigm in cancer drug treatment regimens?

RG Kenny, CJ Marmion - Chemical reviews, 2019 - ACS Publications
While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Stimuli-responsive therapeutic metallodrugs

X Wang, X Wang, S Jin, N Muhammad, Z Guo - Chemical reviews, 2018 - ACS Publications
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

The medicinal chemistry of ferrocene and its derivatives

M Patra, G Gasser - Nature Reviews Chemistry, 2017 - nature.com
Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …

Platinum-containing heterometallic complexes in cancer therapy: advances and perspectives

L Ma, L Li, G Zhu - Inorganic Chemistry Frontiers, 2022 - pubs.rsc.org
Platinum-based anticancer drugs are among the most widely used antineoplastics in clinical
settings. Their therapeutic applications and outcomes are, however, greatly hampered by …

Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

S Issa, A Prandina, N Bedel, P Rongved… - Journal of enzyme …, 2019 - Taylor & Francis
For over half a century, the carbazole skeleton has been the key structural motif of many
biologically active compounds including natural and synthetic products. Carbazoles have …

Monofunctional platinum (II) anticancer agents

S Jin, Y Guo, Z Guo, X Wang - Pharmaceuticals, 2021 - mdpi.com
Platinum-based anticancer drugs represented by cisplatin play important roles in the
treatment of various solid tumors. However, their applications are largely compromised by …

Biosynthesis of Zinc Oxide Nanoparticles Using Plant Extracts of Aloe vera and Hibiscus sabdariffa: Phytochemical, Antibacterial, Antioxidant and Anti-proliferative …

D Mahendiran, G Subash, D Arumai Selvan, D Rehana… - BioNanoScience, 2017 - Springer
The zinc oxide (ZnO) nanoparticles were successfully synthesized by using aqueous
extracts of Aloe vera gel/leaf and Hibiscus sabdariffa leaf, and characterized by FT IR, UV …

Glucose-appended platinum (II)-BODIPY conjugates for targeted photodynamic therapy in red light

V Ramu, S Gautam, A Garai, P Kondaiah… - Inorganic …, 2018 - ACS Publications
Platinum (II) complexes [Pt (L1)(R-BODIPY)] Cl (1) and [Pt (L2)(R-BODIPY)] Cl (2), where R-
BODIPY is 8-(4-ethynylphenyl)-distyryl-4, 4-difluoro-5, 7-dimethyl-4-bora-3a, 4a-diaza-s …

Platinum (II) terpyridine anticancer complexes possessing multiple mode of DNA interaction and EGFR inhibiting activity

C Li, F Xu, Y Zhao, W Zheng, W Zeng, Q Luo… - Frontiers in …, 2020 - frontiersin.org
Platinum (II) terpyridine complexes has attracted increasing attention as they have displayed
great potential as antitumor agents due to their high intercalation affinity with nucleic acids …

Synthesis of Ni (II) complexes bearing indole-based thiosemicarbazone ligands for interaction with biomolecules and some biological applications

J Haribabu, K Jeyalakshmi, Y Arun… - JBIC Journal of …, 2017 - Springer
A series of new Ni (II) complexes containing indole-based thiosemicarbazone ligands was
synthesized and characterized by elemental analyses, and UV–visible, FT-IR, 1 H & 13 C …