Toward multi-targeted platinum and ruthenium drugs—a new paradigm in cancer drug treatment regimens?
RG Kenny, CJ Marmion - Chemical reviews, 2019 - ACS Publications
While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …
the late 1800s when Alfred Werner published his ground-breaking research on coordination …
Stimuli-responsive therapeutic metallodrugs
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …
metal-based drugs for several decades, whereas problems such as drug-resistance and …
The medicinal chemistry of ferrocene and its derivatives
Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …
Platinum-containing heterometallic complexes in cancer therapy: advances and perspectives
L Ma, L Li, G Zhu - Inorganic Chemistry Frontiers, 2022 - pubs.rsc.org
Platinum-based anticancer drugs are among the most widely used antineoplastics in clinical
settings. Their therapeutic applications and outcomes are, however, greatly hampered by …
settings. Their therapeutic applications and outcomes are, however, greatly hampered by …
Carbazole scaffolds in cancer therapy: a review from 2012 to 2018
For over half a century, the carbazole skeleton has been the key structural motif of many
biologically active compounds including natural and synthetic products. Carbazoles have …
biologically active compounds including natural and synthetic products. Carbazoles have …
Monofunctional platinum (II) anticancer agents
S Jin, Y Guo, Z Guo, X Wang - Pharmaceuticals, 2021 - mdpi.com
Platinum-based anticancer drugs represented by cisplatin play important roles in the
treatment of various solid tumors. However, their applications are largely compromised by …
treatment of various solid tumors. However, their applications are largely compromised by …
Biosynthesis of Zinc Oxide Nanoparticles Using Plant Extracts of Aloe vera and Hibiscus sabdariffa: Phytochemical, Antibacterial, Antioxidant and Anti-proliferative …
D Mahendiran, G Subash, D Arumai Selvan, D Rehana… - BioNanoScience, 2017 - Springer
The zinc oxide (ZnO) nanoparticles were successfully synthesized by using aqueous
extracts of Aloe vera gel/leaf and Hibiscus sabdariffa leaf, and characterized by FT IR, UV …
extracts of Aloe vera gel/leaf and Hibiscus sabdariffa leaf, and characterized by FT IR, UV …
Glucose-appended platinum (II)-BODIPY conjugates for targeted photodynamic therapy in red light
V Ramu, S Gautam, A Garai, P Kondaiah… - Inorganic …, 2018 - ACS Publications
Platinum (II) complexes [Pt (L1)(R-BODIPY)] Cl (1) and [Pt (L2)(R-BODIPY)] Cl (2), where R-
BODIPY is 8-(4-ethynylphenyl)-distyryl-4, 4-difluoro-5, 7-dimethyl-4-bora-3a, 4a-diaza-s …
BODIPY is 8-(4-ethynylphenyl)-distyryl-4, 4-difluoro-5, 7-dimethyl-4-bora-3a, 4a-diaza-s …
Platinum (II) terpyridine anticancer complexes possessing multiple mode of DNA interaction and EGFR inhibiting activity
Platinum (II) terpyridine complexes has attracted increasing attention as they have displayed
great potential as antitumor agents due to their high intercalation affinity with nucleic acids …
great potential as antitumor agents due to their high intercalation affinity with nucleic acids …
Synthesis of Ni (II) complexes bearing indole-based thiosemicarbazone ligands for interaction with biomolecules and some biological applications
A series of new Ni (II) complexes containing indole-based thiosemicarbazone ligands was
synthesized and characterized by elemental analyses, and UV–visible, FT-IR, 1 H & 13 C …
synthesized and characterized by elemental analyses, and UV–visible, FT-IR, 1 H & 13 C …