We propose implications as to how this knowledge from natural infection can be applied in
the design and evaluation of CD8+ T-cell-based remission strategies and offer questions to …

The essentially monomorphic human antigen presentation molecule HLA-E is an interesting
candidate target to enable vaccination irrespective of genetic diversity. Predictive HLA-E …

Human leukocyte antigen (HLA)-E binds epitopes derived from HLA-A, HLA-B, HLA-C and
HLA-G signal peptides (SPs) and serves as a ligand for CD94/NKG2A and CD94/NKG2C …

Several studies have shown promise in many preclinical models of disease, including
simian immunodeficiency virus (SIV)/SHIV infection in nonhuman primates and HIV infection …

Although antiretroviral therapy (ART) has drastically changed the lives of people living with
human immunodeficiency virus-1 (HIV-1), long-term treatment has been associated with a …

Immunotherapeutic interventions to enhance natural HIV-specific CD8+ T cell responses,
such as vaccination or adoptive T cell transfer, have been a major focus of HIV cure efforts …

The commonly used antibodies 3D12 and 4D12 recognise the human leukocyte antigen E
(HLA-E) protein. These antibodies bind distinct epitopes on HLA-E and differ in their ability …

Naturally occurring T cells that recognize microbial peptides via HLA-E, a nonpolymorphic
HLA class Ib molecule, could provide the foundation for new universal immunotherapeutics …

Introduction Tuberculosis (TB) remains the first cause of death from infection caused by a
bacterial pathogen. Chemotherapy does not eradicate Mycobacterium tuberculosis (Mtb) …

Recurrent respiratory papillomatosis (RRP), a rare chronic disease caused primarily by
human papillomavirus types 6 and 11, consists of repeated growth of premalignant …