A thriving multi-kingdom microbial ecosystem inhabits the respiratory tract: the respiratory
tract microbiome (RTM). In recent years, the contribution of the RTM to human health has …

Background Bacteria colonizing the upper respiratory tract (URT) of young children play a
key role in the pathogenesis of lower respiratory tract infection (LRTI). Objectives To …

Although previous studies have reported the dysregulation of respiratory tract microbiota in
infectious diseases, insufficient data exist regarding respiratory microbiota imbalances in the …

Background Mycoplasma pneumoniae is a common cause of community-acquired
pneumonia in school-aged children and can be preceded by asymptomatic carriage …

The nasopharyngeal microbiome is a dynamic microbial interface of the aerodigestive tract,
and a diagnostic window in the fight against respiratory infections and antimicrobial …

Healthy lungs were long thought of as sterile, with presence of bacteria identified by culture
representing contamination. Recent advances in metagenomics have refuted this belief by …

Introduction Mycoplasma pneumoniae (MP) is a major pathogen of community-acquired
pneumonia in children. However, the specific pathogenesis of the progression of …

Mycoplasma pneumoniae (MP) is primarily recognized as a respiratory pathogen that
causes community-acquired pneumonia, which can lead to acute upper and lower airway …

Background This study aimed to investigate the interactions among three core elements of
respiratory infection—pathogen, lung microbiome, and host response—and their avocation …

The upper respiratory tract is an obliged pathway for respiratory pathogens and a healthy
microbiota may support the host's mucosal immunity preventing infection. We analyzed the …