Heat shock proteins and viral infection

X Zhang, W Yu - Frontiers in immunology, 2022 - frontiersin.org
Heat shock proteins (HSPs) are a kind of proteins which mostly found in bacterial, plant and
animal cells, in which they are involved in the monitoring and regulation of cellular life …

Targeting dendritic cells with biomaterials: developing the next generation of vaccines

ST Reddy, MA Swartz, JA Hubbell - Trends in immunology, 2006 - cell.com
Current vaccine and immunotherapy technology faces ongoing challenges in both efficacy
and practicality: many chronic diseases cannot yet be addressed by vaccination, and …

Cancer immunotherapy based on intracellular hyperthermia using magnetite nanoparticles: a novel concept of “heat-controlled necrosis” with heat shock protein …

A Ito, H Honda, T Kobayashi - Cancer Immunology, Immunotherapy, 2006 - Springer
Heat shock proteins (HSPs) are highly conserved proteins whose syntheses are induced by
a variety of stresses, including heat stress. Since the expression of HSPs, including HSP70 …

SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling

K Evel-Kabler, XT Song, M Aldrich… - The Journal of …, 2006 - Am Soc Clin Investig
DC-based tumor vaccine research has largely focused on enhancing DC maturation/
costimulation and antigen presentation in order to break tolerance against self tumor …

Heat-shock proteins as powerful weapons in vaccine development

A Bolhassani, S Rafati - Expert review of vaccines, 2008 - Taylor & Francis
Heat-shock proteins (HSPs) have been known as multifunctional proteins. They facilitate the
folding and unfolding of proteins, participate in vesicular transport processes, prevent …

Immunotherapy for cervical cancer: Research status and clinical potential

JH Su, A Wu, E Scotney, B Ma, A Monie, CF Hung… - BioDrugs, 2010 - Springer
The high-risk types of human papillomavirus (HPV) have been found to be associated with
most cervical cancers and play an essential role in the pathogenesis of the disease. Despite …

DNA lipid nanoparticle vaccine targeting outer surface protein C affords protection against homologous Borrelia burgdorferi needle challenge in mice

A Pfeifle, SN Thulasi Raman, C Lansdell… - Frontiers in …, 2023 - frontiersin.org
Introduction The incidence of Lyme disease (LD) in Canada and the United States has risen
over the last decade, nearing 480,000 cases each year. Borrelia burgdorferi sensu lato, the …

DNA vaccines for cervical cancer: from bench to bedside

CF Hung, A Monie, RD Alvarez, TC Wu - Experimental & molecular …, 2007 - nature.com
More than 99% of cervical cancers have been associated with human papillomaviruses
(HPVs), particularly HPV type 16. The clear association between HPV infection and cervical …

Heat shock proteins (HSPs) based anti-cancer vaccines

DR Ciocca, N Cayado-Gutierrez… - Current molecular …, 2012 - ingentaconnect.com
The importance of HSPs themselves in antigen presentation and cross-presentation remains
controversial. Most studies agree that as part of their molecular chaperone function, HSPs …

Biomaterials as vaccine adjuvants

KS Jones - Biotechnology progress, 2008 - Wiley Online Library
Biomaterials are promising candidate adjuvants to enhance vaccine efficacy. Through
adjuvant design, we can broaden the use of vaccines to diseases such as AIDS, malaria …