The diagnosis and management of thyroid nodules: a review

C Durante, G Grani, L Lamartina, S Filetti, SJ Mandel… - Jama, 2018 - jamanetwork.com
Importance Thyroid nodules are common, being detected in up to 65% of the general
population. This is likely due to the increased use of diagnostic imaging for purposes …

Biologic and clinical perspectives on thyroid cancer

JA Fagin, SA Wells Jr - New England Journal of Medicine, 2016 - Mass Medical Soc
Biologic and Clinical Perspectives on Thyroid Cancer | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults

KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Deep learning-based artificial intelligence model to assist thyroid nodule diagnosis and management: a multicentre diagnostic study

S Peng, Y Liu, W Lv, L Liu, Q Zhou, H Yang… - The Lancet Digital …, 2021 - thelancet.com
Background Strategies for integrating artificial intelligence (AI) into thyroid nodule
management require additional development and testing. We developed a deep-learning AI …

Performance of a multigene genomic classifier in thyroid nodules with indeterminate cytology: a prospective blinded multicenter study

DL Steward, SE Carty, RS Sippel, SP Yang… - JAMA …, 2019 - jamanetwork.com
Importance Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have
indeterminate cytology, most frequently Bethesda category III or IV. Diagnostic surgeries can …

NCCN guidelines insights: thyroid carcinoma, version 2.2018

RI Haddad, C Nasr, L Bischoff, NL Busaidy… - Journal of the National …, 2018 - jnccn.org
The NCCN Guidelines for Thyroid Carcinoma provide recommendations for the
management of different types of thyroid carcinoma, including papillary, follicular, Hürthle …

Effectiveness of molecular testing techniques for diagnosis of indeterminate thyroid nodules: a randomized clinical trial

MJ Livhits, CY Zhu, EJ Kuo, DT Nguyen, J Kim… - JAMA …, 2021 - jamanetwork.com
Importance Approximately 20% of thyroid nodules display indeterminate cytology. Molecular
testing can refine the risk of malignancy and reduce the need for diagnostic …

Integrated genomic characterization of papillary thyroid carcinoma

N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi… - Cell, 2014 - cell.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …

[HTML][HTML] Management guidelines for children with thyroid nodules and differentiated thyroid cancer

L FrancisGary, G WaguespackSteven, J BauerAndrew… - Thyroid, 2015 - liebertpub.com
Background: Previous guidelines for the management of thyroid nodules and cancers were
geared toward adults. Compared with thyroid neoplasms in adults, however, those in the …

[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges

SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …